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Interferon gamma mediates the reduction of adipose tissue regulatory T cells in human obesity

Decreased adipose tissue regulatory T cells contribute to insulin resistance in obese mice, however, little is known about the mechanisms regulating adipose tissue regulatory T cells numbers in humans. Here we obtain adipose tissue from obese and lean volunteers. Regulatory T cell abundance is lower...

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Detalles Bibliográficos
Autores principales:	Bradley, David, Smith, Alan J., Blaszczak, Alecia, Shantaram, Dharti, Bergin, Stephen M., Jalilvand, Anahita, Wright, Valerie, Wyne, Kathleen L., Dewal, Revati S., Baer, Lisa A., Wright, Katherine R., Stanford, Kristin I., Needleman, Bradley, Brethauer, Stacy, Noria, Sabrena, Renton, David, Joseph, Joshua J., Lovett-Racke, Amy, Liu, Joey, Hsueh, Willa A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9509397/ https://www.ncbi.nlm.nih.gov/pubmed/36153324 http://dx.doi.org/10.1038/s41467-022-33067-5

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