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Impact of adaptive filtering on power and false discovery rate in RNA-seq experiments
BACKGROUND: In RNA-sequencing studies a large number of hypothesis tests are performed to compare the differential expression of genes between several conditions. Filtering has been proposed to remove candidate genes with a low expression level which may not be relevant and have little or no chance...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9509565/ https://www.ncbi.nlm.nih.gov/pubmed/36153479 http://dx.doi.org/10.1186/s12859-022-04928-z |