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Exosomal AP000439.2 from clear cell renal cell carcinoma induces M2 macrophage polarization to promote tumor progression through activation of STAT3

BACKGROUND: Tumorigenic phenotype of M2 tumor-associated macrophages promote tumor progression in response to exosomes cues imposed by tumor cells. However, the effect and underlying mechanisms of clear cell renal cell carcinoma (ccRCC)-derived exosomes (ccRCC-exo) on instructing macrophages phenoty...

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Detalles Bibliográficos
Autores principales:	Shen, Tianyi, Miao, Suqin, Zhou, Yulin, Yi, Xiaoming, Xue, Song, Du, Bowen, Tang, Chaopeng, Qu, Le, Fu, Dian, Jia, Ruipeng, He, Haowei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9509597/ https://www.ncbi.nlm.nih.gov/pubmed/36153596 http://dx.doi.org/10.1186/s12964-022-00957-6

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