Deep whole genome sequencing identifies recurrent genomic alterations in commonly used breast cancer cell lines and patient-derived xenograft models

BACKGROUND: Breast cancer cell lines (BCCLs) and patient-derived xenografts (PDXs) are the most frequently used models in breast cancer research. Despite their widespread usage, genome sequencing of these models is incomplete, with previous studies only focusing on targeted gene panels, whole exome...

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Detalles Bibliográficos
Autores principales: Deng, Niantao, Minoche, Andre, Harvey, Kate, Li, Meng, Winkler, Juliane, Goga, Andrei, Swarbrick, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9509640/
https://www.ncbi.nlm.nih.gov/pubmed/36153537
http://dx.doi.org/10.1186/s13058-022-01540-0

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