Cargando…

Clinical Efficacy, Antibiotic Resistance Genes, Virulence Factors and Outcome of Hospital-Acquired Pneumonia Induced by Klebsiella pneumoniae Carbapenemase 2-Producing with Tigecycline Treatment in the ICU

PURPOSE: Tigecycline is an agent for carbapenemase-producing Klebsiella pneumonia (KPC-KP), given its penetration into lung tissues. Our study focused on the molecular and clinical efficacy of tigecycline for hospital-acquired pneumonia (HAP) in the ICU. PATIENTS AND METHODS: A retrospective cohort...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bai, Xiang-Rong, Cao, Jing-Rong, Wang, Zhi-Zhou, Li, Wen-Chao, Chen, Dian-Dian, Lou, Ran, Qu, Xin, Yan, Su-Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9509680/ https://www.ncbi.nlm.nih.gov/pubmed/36168639 http://dx.doi.org/10.2147/IDR.S381280

Ejemplares similares

Efficacy of tigecycline, polymyxin, gentamicin, meropenem and associations in experimental Klebsiella pneumoniae carbapenemase-producing Klebsiella pneumoniae non-lethal sepsis
por: Toledo, Paula Virginia Michelon, et al.
Publicado: (2014)

Carbapenemase-producing Klebsiella pneumoniae
por: Robilotti, Elizabeth, et al.
Publicado: (2014)

Carbapenemase-producing Klebsiella pneumoniae intra-abdominal infection successfully treated with ceftazidime/avibactam plus tigecycline
por: Guedes, Mariana, et al.
Publicado: (2020)

Tigecycline Susceptibility and the Role of Efflux Pumps in Tigecycline Resistance in KPC-Producing Klebsiella pneumoniae
por: He, Fang, et al.
Publicado: (2015)

Evaluation of ceftazidime/avibactam alone and in combination with amikacin, colistin and tigecycline against Klebsiella pneumoniae carbapenemase-producing K. pneumoniae by in vitro time-kill experiment
por: Wang, Fangzhou, et al.
Publicado: (2021)

Household Transmission of Carbapenemase-producing Klebsiella pneumoniae
por: Gottesman, Tamar, et al.
Publicado: (2008)

Carbapenemase-producing Klebsiella pneumoniae and Hematologic Malignancies
por: Pagano, Livio, et al.
Publicado: (2014)

Emergence of Tigecycline Nonsusceptible and IMP-4 Carbapenemase-Producing K2-ST65 Hypervirulent Klebsiella pneumoniae in China
por: Zhang, Yawei, et al.
Publicado: (2021)

Klebsiella pneumoniae Carbapenemase-producing Enterobacteria in Hospital, Singapore
por: Venkatachalam, Indumathi, et al.
Publicado: (2012)

Containing Carbapenemase-producing Klebsiella pneumoniae in an endemic setting
por: Spyridopoulou, Kalliopi, et al.
Publicado: (2020)

Molecular Epidemiology of Hypervirulent Carbapenemase-Producing Klebsiella pneumoniae
por: Hu, Dakang, et al.
Publicado: (2021)

Genomic Epidemiology of Carbapenemase-producing Klebsiella pneumoniae in China
por: Li, Cuidan, et al.
Publicado: (2022)

Ceftazidime/Avibactam Resistance in Carbapenemase-Producing Klebsiella pneumoniae
por: Cui, Qiaozhen, et al.
Publicado: (2023)

Sequence-Based Genomic Analysis Reveals Transmission of Antibiotic Resistance and Virulence among Carbapenemase-Producing Klebsiella pneumoniae Strains
por: Zhang, Yi, et al.
Publicado: (2022)

Impact of Tigecycline’s MIC in the Outcome of Critically Ill Patients with Carbapenemase-Producing Klebsiella pneumoniae Bacteraemia Treated with Tigecycline Monotherapy—Validation of 2019′s EUCAST Proposed Breakpoint Changes
por: Papadimitriou-Olivgeris, Matthaios, et al.
Publicado: (2020)

Triple combination antibiotic therapy for carbapenemase-producing Klebsiella pneumoniae: a systematic review
por: Jacobs, David M., et al.
Publicado: (2017)

Klebsiella pneumoniae Carbapenemase, Canada
por: Pillai, Dylan R., et al.
Publicado: (2009)

In vivo Emergence of Colistin and Tigecycline Resistance in Carbapenem-Resistant Hypervirulent Klebsiella pneumoniae During Antibiotics Treatment
por: Chen, Jiawei, et al.
Publicado: (2021)

Within-patient plasmid dynamics in Klebsiella pneumoniae during an outbreak of a carbapenemase-producing Klebsiella pneumoniae
por: Stohr, Joep J. J. M., et al.
Publicado: (2020)

Infections Caused by Carbapenemase-Producing Klebsiella pneumoniae: Microbiological Characteristics and Risk Factors
por: Pan, Hongying, et al.
Publicado: (2019)

Epidemiology of Carbapenemase-Producing Klebsiella pneumoniae in a Hospital, Portugal
por: Aires-de-Sousa, Marta, et al.
Publicado: (2019)

Prevalence of Acquired Carbapenemase Genes in Klebsiella Pneumoniae by Multiplex PCR in Isfahan
por: Khorvash, Farzin, et al.
Publicado: (2017)

Quantifying the clinical virulence of Klebsiella pneumoniae producing carbapenemase Klebsiella pneumoniae with a Galleria mellonella model and a pilot study to translate to patient outcomes
por: McLaughlin, Milena M, et al.
Publicado: (2014)

Complete Genome Sequence of Klebsiella pneumoniae Carbapenemase-Producing K. pneumoniae Siphophage Sushi
por: Nguyen, Dat T., et al.
Publicado: (2015)

Complete Genome Sequence of Klebsiella pneumoniae Carbapenemase-Producing K. pneumoniae Myophage Miro
por: Mijalis, Eleni M., et al.
Publicado: (2015)

Emergence of clinical Klebsiella pneumoniae producing OXA-232 carbapenemase in Singapore
por: Teo, J W P, et al.
Publicado: (2013)

Carbapenemase-Producing Klebsiella pneumoniae in Romania: A Six-Month Survey
por: Lixandru, Brandusa Elena, et al.
Publicado: (2015)

Complete Genome Sequence of Carbapenemase-Producing Klebsiella pneumoniae Myophage Matisse
por: Provasek, Vincent E., et al.
Publicado: (2015)

Klebsiella pneumoniae Carbapenemase Producers in South Korea between 2013 and 2015
por: Yoon, Eun-Jeong, et al.
Publicado: (2018)

Comparison of genotypic and phenotypic antimicrobial profile in carbapenemases producing Klebsiella pneumoniae
por: Del Rio, Arcadia, et al.
Publicado: (2023)

Genomic Epidemiology of an Endoscope-Associated Outbreak of Klebsiella pneumoniae Carbapenemase (KPC)-Producing K. pneumoniae
por: Marsh, Jane W., et al.
Publicado: (2015)

Development of Tigecycline Resistance in Carbapenemase-Producing Klebsiella pneumoniae Sequence Type 147 via AcrAB Overproduction Mediated by Replacement of the ramA Promoter
por: Yoon, Eun-Jeong, et al.
Publicado: (2020)

Formulation of phage cocktails and evaluation of their interaction with antibiotics in inhibiting carbapenemase-producing Klebsiella pneumoniae in vitro in Kenya
por: Michodigni, Noutin F., et al.
Publicado: (2022)

Tracking microevolution events among ST11 carbapenemase-producing hypervirulent Klebsiella pneumoniae outbreak strains
por: Dong, Ning, et al.
Publicado: (2018)

Outbreak Of Klebsiella pneumoniae Carbapenemase-Producing Klebsiella aerogenes Strains In A Tertiary Hospital In China
por: Hao, Min, et al.
Publicado: (2019)

Combined effect of Polymyxin B and Tigecycline to overcome Heteroresistance in Carbapenem-Resistant Klebsiella pneumoniae
por: Tian, Yuan, et al.
Publicado: (2021)

Risk Factors for Mortality in Patients with Klebsiella pneumoniae Carbapenemase-producing K. pneumoniae and Escherichia coli bacteremia
por: Seo, Hyeonji, et al.
Publicado: (2021)

Emergence of Klebsiella pneumoniae clinical isolates producing KPC-2 carbapenemase in Cuba
por: Quiñones, D, et al.
Publicado: (2014)

Nosocomial infections by Klebsiella pneumoniae carbapenemase producing enterobacteria in a teaching hospital
por: Seibert, Gabriela, et al.
Publicado: (2014)

Epidemiology and resistance phenotypes of carbapenemase-producing Klebsiella pneumoniae in Greece, 2014 to 2016
por: Galani, Irene, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_db7a6crte5i0f8qtlhfd1s02p1