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Building a healthy mouse model ecosystem to interrogate cancer biology
In a recent study, Sargent et al. characterise several novel Rag1(−/−) mouse strains and demonstrate that genetic background strongly influences xenograft development and phenotype. Here, we discuss this work within the broader context of cancer mouse modelling. We argue that new technologies will e...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Ltd
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9509886/ https://www.ncbi.nlm.nih.gov/pubmed/36098988 http://dx.doi.org/10.1242/dmm.049795 |