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Runx2 regulates chromatin accessibility to direct the osteoblast program at neonatal stages
The transcriptional regulator Runx2 (runt-related transcription factor 2) has essential but distinct roles in osteoblasts and chondrocytes in skeletal development. However, Runx2-mediated regulatory mechanisms underlying the distinctive programming of osteoblasts and chondrocytes are not well unders...
Autores principales: | Hojo, Hironori, Saito, Taku, He, Xinjun, Guo, Qiuyu, Onodera, Shoko, Azuma, Toshifumi, Koebis, Michinori, Nakao, Kazuki, Aiba, Atsu, Seki, Masahide, Suzuki, Yutaka, Okada, Hiroyuki, Tanaka, Sakae, Chung, Ung-il, McMahon, Andrew P., Ohba, Shinsuke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510047/ https://www.ncbi.nlm.nih.gov/pubmed/36070691 http://dx.doi.org/10.1016/j.celrep.2022.111315 |
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