Longitudinal characterization of circulating neutrophils uncovers phenotypes associated with severity in hospitalized COVID-19 patients

Mechanisms of neutrophil involvement in severe coronavirus disease 2019 (COVID-19) remain incompletely understood. Here, we collect longitudinal blood samples from 306 hospitalized COVID-19(+) patients and 86 controls and perform bulk RNA sequencing of enriched neutrophils, plasma proteomics, and hi...

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Detalles Bibliográficos
Autores principales: LaSalle, Thomas J., Gonye, Anna L.K., Freeman, Samuel S., Kaplonek, Paulina, Gushterova, Irena, Kays, Kyle R., Manakongtreecheep, Kasidet, Tantivit, Jessica, Rojas-Lopez, Maricarmen, Russo, Brian C., Sharma, Nihaarika, Thomas, Molly F., Lavin-Parsons, Kendall M., Lilly, Brendan M., Mckaig, Brenna N., Charland, Nicole C., Khanna, Hargun K., Lodenstein, Carl L., Margolin, Justin D., Blaum, Emily M., Lirofonis, Paola B., Revach, Or-Yam, Mehta, Arnav, Sonny, Abraham, Bhattacharyya, Roby P., Parry, Blair Alden, Goldberg, Marcia B., Alter, Galit, Filbin, Michael R., Villani, Alexandra-Chloé, Hacohen, Nir, Sade-Feldman, Moshe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510054/
https://www.ncbi.nlm.nih.gov/pubmed/36208629
http://dx.doi.org/10.1016/j.xcrm.2022.100779

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