Two pediatric cases of multisystem inflammatory-like syndrome following COVID-19 vaccination

Multisystem inflammatory syndrome in children (MIS-C) is a novel post-infectious disease occurring in the context of SARS-CoV2 infection. COVID-19 vaccines have been authorized since December 2020, and adverse events including myocarditis have been reported following vaccination. We describe the cas...

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Detalles Bibliográficos
Autores principales: Collignon, C., Frachette, C., Callot, D., Pinhas, Y., Bataille, P., Bader-Meunier, B., Chouchana, L., Frémond, M.-L., Belhadjer, Z., Oualha, M., Moulin, F., Javouhey, E., Belot, A., Renolleau, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Masson SAS on behalf of French Society of Pediatrics. 2022
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510064/
https://www.ncbi.nlm.nih.gov/pubmed/36283888
http://dx.doi.org/10.1016/j.arcped.2022.08.018
Descripción
Sumario:Multisystem inflammatory syndrome in children (MIS-C) is a novel post-infectious disease occurring in the context of SARS-CoV2 infection. COVID-19 vaccines have been authorized since December 2020, and adverse events including myocarditis have been reported following vaccination. We describe the cases of two pediatric patients presenting with clinical and laboratory features suggestive of MIS-C a few days after receiving their first dose of the Pfizer BNT162b2 vaccine. The outcome was favorable for both patients (after corticosteroid and immunoglobulin administration for one patient). These cases suggest an association between the COVID-19 vaccine and the occurrence of MIS-C.

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