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Sequence-specific (1)H, (13)C and (15)N backbone NMR assignments for the N-terminal IgV-like domain (D1) and full extracellular region (D1D2) of PD-L1

The co-inhibitory immune checkpoint interaction between programmed cell death-protein 1 (PD-1) and programmed cell death-ligand 1 (PD-L1) serves to regulate T-cell activation, promoting self-tolerance. Over-expression of PD-L1 is a mechanism through which tumour cells can evade detection by the immu...

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Detalles Bibliográficos
Autores principales:	Walker, Kayleigh, Waters, Lorna C., Kelly, Geoff, Muskett, Frederick W., Carr, Mark D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Netherlands 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510113/ https://www.ncbi.nlm.nih.gov/pubmed/35675028 http://dx.doi.org/10.1007/s12104-022-10092-5

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