A comprehensive review on ethnobotanical, medicinal and nutritional potential of walnut (Juglans regia L.)

Juglans regia L. commonly known as walnut is used as the most extensive and economical tree in the world. This review aims to study the ethnomedicinal, phytochemical and pharmacological potential of walnut. The literature has been collected from different online sources like science Direct, Scopus, ResearchGate, Google Scholar, PubMed, etc. based on inclusion and exclusion criteria. An ethnomedicinal survey has also been conducted to document the traditional knowledge and uses of walnut among the local peoples of the Union Territory of Jammu and Kashmir. On surveying the local peoples in the different major walnut-producing areas, it has been followed that the walnut is locally used as a medicinal, nutritional, and commercial plant to treat common diseases and disorders in the locality. The survey has been conducted first time in the area and no study has been reported till now in the Jammu Division while some work has been reported in the Kashmir Division. Among the many bioactive compounds present in various plant parts, Juglone has been reported a significant anti-cancer compound in treating deadly cancer. This systematic review describes the significant knowledge and traditional information collected on ethnomedicinal uses, phytochemistry, habitat, macro-morphology, area of distribution, and pharmacological importance.