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Discrete Models in Epidemiology: New Contagion Probability Functions Based on Real Data Behavior

Mathematical modeling is a tool used for understanding diseases dynamics. The discrete-time model is an especial case in modeling that satisfactorily describes the epidemiological dynamics because of the discrete nature of the real data. However, discrete models reduce their descriptive and fitting...

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Autores principales: Catano-Lopez, Alexandra, Rojas-Diaz, Daniel, Lizarralde-Bejarano, Diana Paola, Puerta Yepes, María Eugenia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510274/
https://www.ncbi.nlm.nih.gov/pubmed/36138179
http://dx.doi.org/10.1007/s11538-022-01076-6
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author Catano-Lopez, Alexandra
Rojas-Diaz, Daniel
Lizarralde-Bejarano, Diana Paola
Puerta Yepes, María Eugenia
author_facet Catano-Lopez, Alexandra
Rojas-Diaz, Daniel
Lizarralde-Bejarano, Diana Paola
Puerta Yepes, María Eugenia
author_sort Catano-Lopez, Alexandra
collection PubMed
description Mathematical modeling is a tool used for understanding diseases dynamics. The discrete-time model is an especial case in modeling that satisfactorily describes the epidemiological dynamics because of the discrete nature of the real data. However, discrete models reduce their descriptive and fitting potential because of assuming a homogeneous population. Thus, in this paper, we proposed contagion probability functions according to two infection paradigms that consider factors associated with transmission dynamics. For example, we introduced probabilities of establishing an infectious interaction, the number of contacts with infectious and the level of connectivity or social distance within populations. Through the probabilities design, we overcame the homogeneity assumption. Also, we evaluated the proposed probabilities through their introduction into discrete-time models for two diseases and different study zones with real data, COVID-19 for Germany and South Korea, and dengue for Colombia. Also, we described the oscillatory dynamics for the last one using the contagion probabilities alongside parameters with a biological sense. Finally, we highlight the implementation of the proposed probabilities would improve the simulation of the public policy effect of control strategies over an infectious disease outbreak.
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spelling pubmed-95102742022-09-26 Discrete Models in Epidemiology: New Contagion Probability Functions Based on Real Data Behavior Catano-Lopez, Alexandra Rojas-Diaz, Daniel Lizarralde-Bejarano, Diana Paola Puerta Yepes, María Eugenia Bull Math Biol Original Article Mathematical modeling is a tool used for understanding diseases dynamics. The discrete-time model is an especial case in modeling that satisfactorily describes the epidemiological dynamics because of the discrete nature of the real data. However, discrete models reduce their descriptive and fitting potential because of assuming a homogeneous population. Thus, in this paper, we proposed contagion probability functions according to two infection paradigms that consider factors associated with transmission dynamics. For example, we introduced probabilities of establishing an infectious interaction, the number of contacts with infectious and the level of connectivity or social distance within populations. Through the probabilities design, we overcame the homogeneity assumption. Also, we evaluated the proposed probabilities through their introduction into discrete-time models for two diseases and different study zones with real data, COVID-19 for Germany and South Korea, and dengue for Colombia. Also, we described the oscillatory dynamics for the last one using the contagion probabilities alongside parameters with a biological sense. Finally, we highlight the implementation of the proposed probabilities would improve the simulation of the public policy effect of control strategies over an infectious disease outbreak. Springer US 2022-09-22 2022 /pmc/articles/PMC9510274/ /pubmed/36138179 http://dx.doi.org/10.1007/s11538-022-01076-6 Text en © The Author(s), under exclusive licence to Society for Mathematical Biology 2022, Springer Nature or its licensor holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Original Article
Catano-Lopez, Alexandra
Rojas-Diaz, Daniel
Lizarralde-Bejarano, Diana Paola
Puerta Yepes, María Eugenia
Discrete Models in Epidemiology: New Contagion Probability Functions Based on Real Data Behavior
title Discrete Models in Epidemiology: New Contagion Probability Functions Based on Real Data Behavior
title_full Discrete Models in Epidemiology: New Contagion Probability Functions Based on Real Data Behavior
title_fullStr Discrete Models in Epidemiology: New Contagion Probability Functions Based on Real Data Behavior
title_full_unstemmed Discrete Models in Epidemiology: New Contagion Probability Functions Based on Real Data Behavior
title_short Discrete Models in Epidemiology: New Contagion Probability Functions Based on Real Data Behavior
title_sort discrete models in epidemiology: new contagion probability functions based on real data behavior
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510274/
https://www.ncbi.nlm.nih.gov/pubmed/36138179
http://dx.doi.org/10.1007/s11538-022-01076-6
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