Paraneoplastische Hyperleukozytose bei Lungenkarzinom

Paraneoplastic leukocytosis in solid tumors is associated with poor prognosis. While mild leukocytosis is common, paraneoplastic hyperleukocytosis is extremely rare. The case of a 73-year-old male diagnosed with an adenocarcinoma of the lung and a peak white blood cell count of 178,000/µl is reporte...

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Detalles Bibliográficos
Autores principales: Heusinger, Josef, Czech, Paul, Hengstler, Heidi, Schaumann, Frank, Rückert, Anja, Schmid, Frank, Kalla, Jörg, Diergardt, Uta, Bremer, Hinrich, La Rosée, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Medizin 2022
Materias:
Kasuistiken
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510345/
https://www.ncbi.nlm.nih.gov/pubmed/36149442
http://dx.doi.org/10.1007/s00108-022-01407-8
Descripción
Sumario:Paraneoplastic leukocytosis in solid tumors is associated with poor prognosis. While mild leukocytosis is common, paraneoplastic hyperleukocytosis is extremely rare. The case of a 73-year-old male diagnosed with an adenocarcinoma of the lung and a peak white blood cell count of 178,000/µl is reported. The patient succumbed to the disease after two cycles of immunochemotherapy only 2 months after first hospital admission. Specific treatment options are still under investigation and have not been reported in clinical use.

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