Paraneoplastische Hyperleukozytose bei Lungenkarzinom

Paraneoplastic leukocytosis in solid tumors is associated with poor prognosis. While mild leukocytosis is common, paraneoplastic hyperleukocytosis is extremely rare. The case of a 73-year-old male diagnosed with an adenocarcinoma of the lung and a peak white blood cell count of 178,000/µl is reporte...

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Autores principales: Heusinger, Josef, Czech, Paul, Hengstler, Heidi, Schaumann, Frank, Rückert, Anja, Schmid, Frank, Kalla, Jörg, Diergardt, Uta, Bremer, Hinrich, La Rosée, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Medizin 2022
Materias:
Kasuistiken
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510345/
https://www.ncbi.nlm.nih.gov/pubmed/36149442
http://dx.doi.org/10.1007/s00108-022-01407-8
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author Heusinger, Josef
Czech, Paul
Hengstler, Heidi
Schaumann, Frank
Rückert, Anja
Schmid, Frank
Kalla, Jörg
Diergardt, Uta
Bremer, Hinrich
La Rosée, Paul
author_facet Heusinger, Josef
Czech, Paul
Hengstler, Heidi
Schaumann, Frank
Rückert, Anja
Schmid, Frank
Kalla, Jörg
Diergardt, Uta
Bremer, Hinrich
La Rosée, Paul
author_sort Heusinger, Josef
collection PubMed
description Paraneoplastic leukocytosis in solid tumors is associated with poor prognosis. While mild leukocytosis is common, paraneoplastic hyperleukocytosis is extremely rare. The case of a 73-year-old male diagnosed with an adenocarcinoma of the lung and a peak white blood cell count of 178,000/µl is reported. The patient succumbed to the disease after two cycles of immunochemotherapy only 2 months after first hospital admission. Specific treatment options are still under investigation and have not been reported in clinical use.
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spelling pubmed-95103452022-09-26 Paraneoplastische Hyperleukozytose bei Lungenkarzinom Heusinger, Josef Czech, Paul Hengstler, Heidi Schaumann, Frank Rückert, Anja Schmid, Frank Kalla, Jörg Diergardt, Uta Bremer, Hinrich La Rosée, Paul Inn Med (Heidelb) Kasuistiken Paraneoplastic leukocytosis in solid tumors is associated with poor prognosis. While mild leukocytosis is common, paraneoplastic hyperleukocytosis is extremely rare. The case of a 73-year-old male diagnosed with an adenocarcinoma of the lung and a peak white blood cell count of 178,000/µl is reported. The patient succumbed to the disease after two cycles of immunochemotherapy only 2 months after first hospital admission. Specific treatment options are still under investigation and have not been reported in clinical use. Springer Medizin 2022-09-23 2022 /pmc/articles/PMC9510345/ /pubmed/36149442 http://dx.doi.org/10.1007/s00108-022-01407-8 Text en © The Author(s), under exclusive licence to Springer Medizin Verlag GmbH, ein Teil von Springer Nature 2022 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Kasuistiken
Heusinger, Josef
Czech, Paul
Hengstler, Heidi
Schaumann, Frank
Rückert, Anja
Schmid, Frank
Kalla, Jörg
Diergardt, Uta
Bremer, Hinrich
La Rosée, Paul
Paraneoplastische Hyperleukozytose bei Lungenkarzinom
title Paraneoplastische Hyperleukozytose bei Lungenkarzinom
title_full Paraneoplastische Hyperleukozytose bei Lungenkarzinom
title_fullStr Paraneoplastische Hyperleukozytose bei Lungenkarzinom
title_full_unstemmed Paraneoplastische Hyperleukozytose bei Lungenkarzinom
title_short Paraneoplastische Hyperleukozytose bei Lungenkarzinom
title_sort paraneoplastische hyperleukozytose bei lungenkarzinom
topic Kasuistiken
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510345/
https://www.ncbi.nlm.nih.gov/pubmed/36149442
http://dx.doi.org/10.1007/s00108-022-01407-8
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