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Effect of Movement on the Early Phase of an Epidemic
The early phase of an epidemic is characterized by a small number of infected individuals, implying that stochastic effects drive the dynamics of the disease. Mathematically, we define the stochastic phase as the time during which the number of infected individuals remains small and positive. A cont...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510491/ https://www.ncbi.nlm.nih.gov/pubmed/36149585 http://dx.doi.org/10.1007/s11538-022-01077-5 |
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author | Arino, Julien Milliken, Evan |
author_facet | Arino, Julien Milliken, Evan |
author_sort | Arino, Julien |
collection | PubMed |
description | The early phase of an epidemic is characterized by a small number of infected individuals, implying that stochastic effects drive the dynamics of the disease. Mathematically, we define the stochastic phase as the time during which the number of infected individuals remains small and positive. A continuous-time Markov chain model of a simple two-patch epidemic is presented. An algorithm for formalizing what is meant by small is presented, and the effect of movement on the duration of the early stochastic phase of an epidemic is studied. |
format | Online Article Text |
id | pubmed-9510491 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Springer US |
record_format | MEDLINE/PubMed |
spelling | pubmed-95104912022-09-26 Effect of Movement on the Early Phase of an Epidemic Arino, Julien Milliken, Evan Bull Math Biol Original Article The early phase of an epidemic is characterized by a small number of infected individuals, implying that stochastic effects drive the dynamics of the disease. Mathematically, we define the stochastic phase as the time during which the number of infected individuals remains small and positive. A continuous-time Markov chain model of a simple two-patch epidemic is presented. An algorithm for formalizing what is meant by small is presented, and the effect of movement on the duration of the early stochastic phase of an epidemic is studied. Springer US 2022-09-23 2022 /pmc/articles/PMC9510491/ /pubmed/36149585 http://dx.doi.org/10.1007/s11538-022-01077-5 Text en © The Author(s), under exclusive licence to Society for Mathematical Biology 2022, Springer Nature or its licensor holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Original Article Arino, Julien Milliken, Evan Effect of Movement on the Early Phase of an Epidemic |
title | Effect of Movement on the Early Phase of an Epidemic |
title_full | Effect of Movement on the Early Phase of an Epidemic |
title_fullStr | Effect of Movement on the Early Phase of an Epidemic |
title_full_unstemmed | Effect of Movement on the Early Phase of an Epidemic |
title_short | Effect of Movement on the Early Phase of an Epidemic |
title_sort | effect of movement on the early phase of an epidemic |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510491/ https://www.ncbi.nlm.nih.gov/pubmed/36149585 http://dx.doi.org/10.1007/s11538-022-01077-5 |
work_keys_str_mv | AT arinojulien effectofmovementontheearlyphaseofanepidemic AT millikenevan effectofmovementontheearlyphaseofanepidemic |