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Modulation of CD19 surface expression in B cell acute lymphoblastic leukemia

Immunotherapeutic targeting of the surface glycoprotein CD19 has markedly improved outcomes in patients with relapsed and refractory B cell progenitor acute lymphoblastic leukemia. Genome-wide CRISPR–Cas9 screening identifies modulators of CD19 mRNA processing that affect the abundance of the surfac...

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Detalles Bibliográficos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group US 2022
Materias:	Research Briefing
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510525/ https://www.ncbi.nlm.nih.gov/pubmed/36151397 http://dx.doi.org/10.1038/s41590-022-01316-w

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