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Geography, niches, and transportation influence bovine respiratory microbiome and health

Bovine respiratory disease (BRD), one of the most common and infectious diseases in the beef industry, is associated with the respiratory microbiome and stressors of transportation. The impacts of the bovine respiratory microbiota on health and disease across different geographic locations and sampl...

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Autores principales: Chai, Jianmin, Liu, Xinting, Usdrowski, Hunter, Deng, Feilong, Li, Ying, Zhao, Jiangchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510686/
https://www.ncbi.nlm.nih.gov/pubmed/36171758
http://dx.doi.org/10.3389/fcimb.2022.961644
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author Chai, Jianmin
Liu, Xinting
Usdrowski, Hunter
Deng, Feilong
Li, Ying
Zhao, Jiangchao
author_facet Chai, Jianmin
Liu, Xinting
Usdrowski, Hunter
Deng, Feilong
Li, Ying
Zhao, Jiangchao
author_sort Chai, Jianmin
collection PubMed
description Bovine respiratory disease (BRD), one of the most common and infectious diseases in the beef industry, is associated with the respiratory microbiome and stressors of transportation. The impacts of the bovine respiratory microbiota on health and disease across different geographic locations and sampling niches are poorly understood, resulting in difficult identification of BRD causes. In this study, we explored the effects of geography and niches on the bovine respiratory microbiome and its function by re-analyzing published metagenomic datasets and estimated the main opportunistic pathogens that changed after transportation. The results showed that diversity, composition, structure, and function of the bovine nasopharyngeal microbiota were different across three worldwide geographic locations. The lung microbiota also showed distinct microbial composition and function compared with nasopharyngeal communities from different locations. Although different signature microbiota for each geographic location were identified, a module with co-occurrence of Mycoplasma species was observed in all bovine respiratory communities regardless of geography. Moreover, transportation, especially long-distance shipping, could increase the relative abundance of BRD-associated pathogens. Lung microbiota from BRD calves shaped clusters dominated with different pathogens. In summary, geography, sampling niches, and transportation are important factors impacting the bovine respiratory microbiome and disease, and clusters of lung microbiota by different bacterial species may explain BRD pathogenesis, suggesting the importance of a deeper understanding of bovine respiratory microbiota in health.
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spelling pubmed-95106862022-09-27 Geography, niches, and transportation influence bovine respiratory microbiome and health Chai, Jianmin Liu, Xinting Usdrowski, Hunter Deng, Feilong Li, Ying Zhao, Jiangchao Front Cell Infect Microbiol Cellular and Infection Microbiology Bovine respiratory disease (BRD), one of the most common and infectious diseases in the beef industry, is associated with the respiratory microbiome and stressors of transportation. The impacts of the bovine respiratory microbiota on health and disease across different geographic locations and sampling niches are poorly understood, resulting in difficult identification of BRD causes. In this study, we explored the effects of geography and niches on the bovine respiratory microbiome and its function by re-analyzing published metagenomic datasets and estimated the main opportunistic pathogens that changed after transportation. The results showed that diversity, composition, structure, and function of the bovine nasopharyngeal microbiota were different across three worldwide geographic locations. The lung microbiota also showed distinct microbial composition and function compared with nasopharyngeal communities from different locations. Although different signature microbiota for each geographic location were identified, a module with co-occurrence of Mycoplasma species was observed in all bovine respiratory communities regardless of geography. Moreover, transportation, especially long-distance shipping, could increase the relative abundance of BRD-associated pathogens. Lung microbiota from BRD calves shaped clusters dominated with different pathogens. In summary, geography, sampling niches, and transportation are important factors impacting the bovine respiratory microbiome and disease, and clusters of lung microbiota by different bacterial species may explain BRD pathogenesis, suggesting the importance of a deeper understanding of bovine respiratory microbiota in health. Frontiers Media S.A. 2022-09-12 /pmc/articles/PMC9510686/ /pubmed/36171758 http://dx.doi.org/10.3389/fcimb.2022.961644 Text en Copyright © 2022 Chai, Liu, Usdrowski, Deng, Li and Zhao https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cellular and Infection Microbiology
Chai, Jianmin
Liu, Xinting
Usdrowski, Hunter
Deng, Feilong
Li, Ying
Zhao, Jiangchao
Geography, niches, and transportation influence bovine respiratory microbiome and health
title Geography, niches, and transportation influence bovine respiratory microbiome and health
title_full Geography, niches, and transportation influence bovine respiratory microbiome and health
title_fullStr Geography, niches, and transportation influence bovine respiratory microbiome and health
title_full_unstemmed Geography, niches, and transportation influence bovine respiratory microbiome and health
title_short Geography, niches, and transportation influence bovine respiratory microbiome and health
title_sort geography, niches, and transportation influence bovine respiratory microbiome and health
topic Cellular and Infection Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510686/
https://www.ncbi.nlm.nih.gov/pubmed/36171758
http://dx.doi.org/10.3389/fcimb.2022.961644
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