Cargando…

Cranial thoracic myelopathies (T1-T6 vertebrae): Retrospective evaluation of the signalment, clinical presentation, and, presumptive or final diagnoses in 84 dogs

The aim of the study was to describe the signalment, clinical presentation and presumptive or final diagnoses of dogs with cranial thoracic spinal cord lesions identified on advanced imaging. Retrospective evaluation of the databases of three veterinary specialty centres, between 2009 and 2021, was...

Descripción completa

Detalles Bibliográficos
Autores principales: Lopes, Bruno A., Ives, Edward J., José-López, Roberto, Gutierrez-Quintana, Rodrigo, Abouzeid, Jad, Freeman, Paul, Redondo, José Ignacio, Sánchez-Masián, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510707/
https://www.ncbi.nlm.nih.gov/pubmed/36172605
http://dx.doi.org/10.3389/fvets.2022.960912
_version_ 1784797497962528768
author Lopes, Bruno A.
Ives, Edward J.
José-López, Roberto
Gutierrez-Quintana, Rodrigo
Abouzeid, Jad
Freeman, Paul
Redondo, José Ignacio
Sánchez-Masián, Daniel
author_facet Lopes, Bruno A.
Ives, Edward J.
José-López, Roberto
Gutierrez-Quintana, Rodrigo
Abouzeid, Jad
Freeman, Paul
Redondo, José Ignacio
Sánchez-Masián, Daniel
author_sort Lopes, Bruno A.
collection PubMed
description The aim of the study was to describe the signalment, clinical presentation and presumptive or final diagnoses of dogs with cranial thoracic spinal cord lesions identified on advanced imaging. Retrospective evaluation of the databases of three veterinary specialty centres, between 2009 and 2021, was performed to identify dogs with a lesion affecting the cranial thoracic vertebral column (T1-T6 vertebrae) as the primary cause for presenting signs of myelopathy and/or spinal pain. Eighty-four dogs were included in the study, with the majority (n = 76) presenting with a progressive history of over 4-weeks' duration. On neurologic examination, most dogs were ambulatory (n = 64), and the most common neuroanatomic localisation was the T3-L3 spinal cord segments (n = 63). Twelve dogs (14%) showed a short-strided thoracic limb gait on clinical examination. The most common diagnosis was neoplasia (n = 33), followed by anomalies (n = 22, including vertebral body malformations in 14 dogs) and degenerative disorders (n = 16, with intervertebral disc protrusion diagnosed in 9 dogs). The most common vertebrae affected were T3 and T5. Most dogs with degenerative conditions showed asymmetric clinical signs, and the majority of dogs with neoplasia showed signs of spinal hyperaesthesia on examination. The findings of this study describe the clinical signs and presumptive or final diagnoses associated with lesions affecting the cranial thoracic spinal cord. When combined with the signalment and clinical history, this information can assist in both the recognition of and problem-based approach to these cases.
format Online
Article
Text
id pubmed-9510707
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-95107072022-09-27 Cranial thoracic myelopathies (T1-T6 vertebrae): Retrospective evaluation of the signalment, clinical presentation, and, presumptive or final diagnoses in 84 dogs Lopes, Bruno A. Ives, Edward J. José-López, Roberto Gutierrez-Quintana, Rodrigo Abouzeid, Jad Freeman, Paul Redondo, José Ignacio Sánchez-Masián, Daniel Front Vet Sci Veterinary Science The aim of the study was to describe the signalment, clinical presentation and presumptive or final diagnoses of dogs with cranial thoracic spinal cord lesions identified on advanced imaging. Retrospective evaluation of the databases of three veterinary specialty centres, between 2009 and 2021, was performed to identify dogs with a lesion affecting the cranial thoracic vertebral column (T1-T6 vertebrae) as the primary cause for presenting signs of myelopathy and/or spinal pain. Eighty-four dogs were included in the study, with the majority (n = 76) presenting with a progressive history of over 4-weeks' duration. On neurologic examination, most dogs were ambulatory (n = 64), and the most common neuroanatomic localisation was the T3-L3 spinal cord segments (n = 63). Twelve dogs (14%) showed a short-strided thoracic limb gait on clinical examination. The most common diagnosis was neoplasia (n = 33), followed by anomalies (n = 22, including vertebral body malformations in 14 dogs) and degenerative disorders (n = 16, with intervertebral disc protrusion diagnosed in 9 dogs). The most common vertebrae affected were T3 and T5. Most dogs with degenerative conditions showed asymmetric clinical signs, and the majority of dogs with neoplasia showed signs of spinal hyperaesthesia on examination. The findings of this study describe the clinical signs and presumptive or final diagnoses associated with lesions affecting the cranial thoracic spinal cord. When combined with the signalment and clinical history, this information can assist in both the recognition of and problem-based approach to these cases. Frontiers Media S.A. 2022-09-12 /pmc/articles/PMC9510707/ /pubmed/36172605 http://dx.doi.org/10.3389/fvets.2022.960912 Text en Copyright © 2022 Lopes, Ives, José-López, Gutierrez-Quintana, Abouzeid, Freeman, Redondo and Sánchez-Masián. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Veterinary Science
Lopes, Bruno A.
Ives, Edward J.
José-López, Roberto
Gutierrez-Quintana, Rodrigo
Abouzeid, Jad
Freeman, Paul
Redondo, José Ignacio
Sánchez-Masián, Daniel
Cranial thoracic myelopathies (T1-T6 vertebrae): Retrospective evaluation of the signalment, clinical presentation, and, presumptive or final diagnoses in 84 dogs
title Cranial thoracic myelopathies (T1-T6 vertebrae): Retrospective evaluation of the signalment, clinical presentation, and, presumptive or final diagnoses in 84 dogs
title_full Cranial thoracic myelopathies (T1-T6 vertebrae): Retrospective evaluation of the signalment, clinical presentation, and, presumptive or final diagnoses in 84 dogs
title_fullStr Cranial thoracic myelopathies (T1-T6 vertebrae): Retrospective evaluation of the signalment, clinical presentation, and, presumptive or final diagnoses in 84 dogs
title_full_unstemmed Cranial thoracic myelopathies (T1-T6 vertebrae): Retrospective evaluation of the signalment, clinical presentation, and, presumptive or final diagnoses in 84 dogs
title_short Cranial thoracic myelopathies (T1-T6 vertebrae): Retrospective evaluation of the signalment, clinical presentation, and, presumptive or final diagnoses in 84 dogs
title_sort cranial thoracic myelopathies (t1-t6 vertebrae): retrospective evaluation of the signalment, clinical presentation, and, presumptive or final diagnoses in 84 dogs
topic Veterinary Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510707/
https://www.ncbi.nlm.nih.gov/pubmed/36172605
http://dx.doi.org/10.3389/fvets.2022.960912
work_keys_str_mv AT lopesbrunoa cranialthoracicmyelopathiest1t6vertebraeretrospectiveevaluationofthesignalmentclinicalpresentationandpresumptiveorfinaldiagnosesin84dogs
AT ivesedwardj cranialthoracicmyelopathiest1t6vertebraeretrospectiveevaluationofthesignalmentclinicalpresentationandpresumptiveorfinaldiagnosesin84dogs
AT joselopezroberto cranialthoracicmyelopathiest1t6vertebraeretrospectiveevaluationofthesignalmentclinicalpresentationandpresumptiveorfinaldiagnosesin84dogs
AT gutierrezquintanarodrigo cranialthoracicmyelopathiest1t6vertebraeretrospectiveevaluationofthesignalmentclinicalpresentationandpresumptiveorfinaldiagnosesin84dogs
AT abouzeidjad cranialthoracicmyelopathiest1t6vertebraeretrospectiveevaluationofthesignalmentclinicalpresentationandpresumptiveorfinaldiagnosesin84dogs
AT freemanpaul cranialthoracicmyelopathiest1t6vertebraeretrospectiveevaluationofthesignalmentclinicalpresentationandpresumptiveorfinaldiagnosesin84dogs
AT redondojoseignacio cranialthoracicmyelopathiest1t6vertebraeretrospectiveevaluationofthesignalmentclinicalpresentationandpresumptiveorfinaldiagnosesin84dogs
AT sanchezmasiandaniel cranialthoracicmyelopathiest1t6vertebraeretrospectiveevaluationofthesignalmentclinicalpresentationandpresumptiveorfinaldiagnosesin84dogs