Integration of single-cell and bulk RNA-seq to establish a predictive signature based on the differentiation trajectory of M2 macrophages in lung adenocarcinoma

Background: Tumor-associated macrophages as important members of the tumor microenvironment, are highly plastic and heterogeneous. TAMs can be classified into two preliminary subtypes: M1 and M2 macrophages. M2 macrophages are significantly associated with the progression of lung adenocarcinoma. How...

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Detalles Bibliográficos
Autores principales: Chen, Zhike, Yang, Jian, Li, Yu, Zeng, Weibiao, Bai, Yiling, Ding, Cheng, Xu, Chun, Li, Chang, Chen, Jun, Ju, Sheng, Tang, Lijuan, Zhao, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510778/
https://www.ncbi.nlm.nih.gov/pubmed/36171876
http://dx.doi.org/10.3389/fgene.2022.1010440

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