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Resequencing 250 Soybean Accessions: New Insights into Genes Associated with Agronomic Traits and Genetic Networks
The limited knowledge of genomic diversity and functional genes associated with the traits of soybean varieties has resulted in slow progress in breeding. In this study, we sequenced the genomes of 250 soybean landraces and cultivars from China, America, and Europe, and investigated their population...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510855/ https://www.ncbi.nlm.nih.gov/pubmed/34314874 http://dx.doi.org/10.1016/j.gpb.2021.02.009 |
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author | Yang, Chunming Yan, Jun Jiang, Shuqin Li, Xia Min, Haowei Wang, Xiangfeng Hao, Dongyun |
author_facet | Yang, Chunming Yan, Jun Jiang, Shuqin Li, Xia Min, Haowei Wang, Xiangfeng Hao, Dongyun |
author_sort | Yang, Chunming |
collection | PubMed |
description | The limited knowledge of genomic diversity and functional genes associated with the traits of soybean varieties has resulted in slow progress in breeding. In this study, we sequenced the genomes of 250 soybean landraces and cultivars from China, America, and Europe, and investigated their population structure, genetic diversity and architecture, and the selective sweep regions of these accessions. Five novel agronomically important genes were identified, and the effects of functional mutations in respective genes were examined. The candidate genes GSTT1, GL3, and GSTL3 associated with the isoflavone content, CKX3 associated with yield traits, and CYP85A2 associated with both architecture and yield traits were found. The phenotype–gene network analysis revealed that hub nodes play a crucial role in complex phenotypic associations. This study describes novel agronomic trait-associated genes and a complex genetic network, providing a valuable resource for future soybean molecular breeding. |
format | Online Article Text |
id | pubmed-9510855 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-95108552022-09-27 Resequencing 250 Soybean Accessions: New Insights into Genes Associated with Agronomic Traits and Genetic Networks Yang, Chunming Yan, Jun Jiang, Shuqin Li, Xia Min, Haowei Wang, Xiangfeng Hao, Dongyun Genomics Proteomics Bioinformatics Original Research The limited knowledge of genomic diversity and functional genes associated with the traits of soybean varieties has resulted in slow progress in breeding. In this study, we sequenced the genomes of 250 soybean landraces and cultivars from China, America, and Europe, and investigated their population structure, genetic diversity and architecture, and the selective sweep regions of these accessions. Five novel agronomically important genes were identified, and the effects of functional mutations in respective genes were examined. The candidate genes GSTT1, GL3, and GSTL3 associated with the isoflavone content, CKX3 associated with yield traits, and CYP85A2 associated with both architecture and yield traits were found. The phenotype–gene network analysis revealed that hub nodes play a crucial role in complex phenotypic associations. This study describes novel agronomic trait-associated genes and a complex genetic network, providing a valuable resource for future soybean molecular breeding. Elsevier 2022-02 2021-07-24 /pmc/articles/PMC9510855/ /pubmed/34314874 http://dx.doi.org/10.1016/j.gpb.2021.02.009 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Original Research Yang, Chunming Yan, Jun Jiang, Shuqin Li, Xia Min, Haowei Wang, Xiangfeng Hao, Dongyun Resequencing 250 Soybean Accessions: New Insights into Genes Associated with Agronomic Traits and Genetic Networks |
title | Resequencing 250 Soybean Accessions: New Insights into Genes Associated with Agronomic Traits and Genetic Networks |
title_full | Resequencing 250 Soybean Accessions: New Insights into Genes Associated with Agronomic Traits and Genetic Networks |
title_fullStr | Resequencing 250 Soybean Accessions: New Insights into Genes Associated with Agronomic Traits and Genetic Networks |
title_full_unstemmed | Resequencing 250 Soybean Accessions: New Insights into Genes Associated with Agronomic Traits and Genetic Networks |
title_short | Resequencing 250 Soybean Accessions: New Insights into Genes Associated with Agronomic Traits and Genetic Networks |
title_sort | resequencing 250 soybean accessions: new insights into genes associated with agronomic traits and genetic networks |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510855/ https://www.ncbi.nlm.nih.gov/pubmed/34314874 http://dx.doi.org/10.1016/j.gpb.2021.02.009 |
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