Npac Is A Co-factor of Histone H3K36me3 and Regulates Transcriptional Elongation in Mouse Embryonic Stem Cells

Chromatin modification contributes to pluripotency maintenance in embryonic stem cells (ESCs). However, the related mechanisms remain obscure. Here, we show that Npac, a “reader” of histone H3 lysine 36 trimethylation (H3K36me3), is required to maintain mouse ESC (mESC) pluripotency since knockdown...

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Detalles Bibliográficos
Autores principales: Yu, Sue, Li, Jia, Ji, Guanxu, Ng, Zhen Long, Siew, Jiamin, Lo, Wan Ning, Ye, Ying, Chew, Yuan Yuan, Long, Yun Chau, Zhang, Wensheng, Guccione, Ernesto, Loh, Yuin Han, Jiang, Zhi-Hong, Yang, Henry, Wu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510873/
https://www.ncbi.nlm.nih.gov/pubmed/33676077
http://dx.doi.org/10.1016/j.gpb.2020.08.004

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