Detection of BRCA1/2 pathogenic variants in patients with breast and/or ovarian cancer and their families. Analysis of 3,458 cases from Lower Silesia (Poland) according to the diagnostic algorithm of the National Cancer Control Programme

Breast and ovarian cancers are among the most common malignancies in the female population, with approximately 5–10% of cases being hereditary. BRCA1 and BRCA2 with other homologous recombination genes are the most tested genes in hereditary breast and ovarian cancer (HBOC) patients. As next-generat...

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Detalles Bibliográficos
Autores principales: Doraczynska-Kowalik, Anna, Michalowska, Dagmara, Matkowski, Rafal, Czykalko, Ewelina, Blomka, Dorota, Semeniuk, Mariola, Abrahamowska, Mariola, Janus-Szymanska, Gabriela, Mlynarczykowska, Paulina, Szynglarewicz, Bartlomiej, Pawlak, Ireneusz, Maciejczyk, Adam, Laczmanska, Izabela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510890/
https://www.ncbi.nlm.nih.gov/pubmed/36171877
http://dx.doi.org/10.3389/fgene.2022.941375

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