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Inorganic phosphate accelerates cardiac myofilament relaxation in response to lengthening

Myocardial relaxation in late systole is enhanced by increasing velocities of lengthening. Given that inorganic phosphate (Pi) can rebind to the force-producing myosin enzyme prior to MgADP release and hasten crossbridge detachment, we hypothesized that myocardial relaxation in late systole would be...

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Detalles Bibliográficos
Autores principales:	Wakefield, Jane I., Bell, Stephen P., Palmer, Bradley M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510985/ https://www.ncbi.nlm.nih.gov/pubmed/36171969 http://dx.doi.org/10.3389/fphys.2022.980662

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