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ACVIM consensus statement on diagnosis and management of acute canine thoracolumbar intervertebral disc extrusion

BACKGROUND: Thoracolumbar intervertebral disc extrusion (TL‐IVDE) is the most common cause of acute paraparesis and paraplegia in dogs; however, guidelines on management of the condition are lacking. OBJECTIVES: To summarize the current literature as it relates to diagnosis and management of acute T...

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Autores principales: Olby, Natasha J., Moore, Sarah A., Brisson, Brigitte, Fenn, Joe, Flegel, Thomas, Kortz, Gregg, Lewis, Melissa, Tipold, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9511077/
https://www.ncbi.nlm.nih.gov/pubmed/35880267
http://dx.doi.org/10.1111/jvim.16480
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author Olby, Natasha J.
Moore, Sarah A.
Brisson, Brigitte
Fenn, Joe
Flegel, Thomas
Kortz, Gregg
Lewis, Melissa
Tipold, Andrea
author_facet Olby, Natasha J.
Moore, Sarah A.
Brisson, Brigitte
Fenn, Joe
Flegel, Thomas
Kortz, Gregg
Lewis, Melissa
Tipold, Andrea
author_sort Olby, Natasha J.
collection PubMed
description BACKGROUND: Thoracolumbar intervertebral disc extrusion (TL‐IVDE) is the most common cause of acute paraparesis and paraplegia in dogs; however, guidelines on management of the condition are lacking. OBJECTIVES: To summarize the current literature as it relates to diagnosis and management of acute TL‐IVDE in dogs, and to formulate clinically relevant evidence‐based recommendations. ANIMALS: None. METHODS: A panel of 8 experts was convened to assess and summarize evidence from the peer‐reviewed literature in order to develop consensus clinical recommendations. Level of evidence available to support each recommendation was assessed and reported. RESULTS: The majority of available literature described observational studies. Most recommendations made by the panel were supported by a low or moderate level of evidence, and several areas of high need for further study were identified. These include better understanding of the ideal timing for surgical decompression, expected surgical vs medical outcomes for more mildly affected dogs, impact of durotomy on locomotor outcome and development of progressive myelomalacia, and refining of postoperative care, and genetic and preventative care studies. CONCLUSIONS AND CLINICAL IMPORTANCE: Future efforts should build on current recommendations by conducting prospective studies and randomized controlled trials, where possible, to address identified gaps in knowledge and to develop cost effectiveness and number needed to treat studies supporting various aspects of diagnosis and treatment of TL‐IVDE.
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spelling pubmed-95110772022-09-30 ACVIM consensus statement on diagnosis and management of acute canine thoracolumbar intervertebral disc extrusion Olby, Natasha J. Moore, Sarah A. Brisson, Brigitte Fenn, Joe Flegel, Thomas Kortz, Gregg Lewis, Melissa Tipold, Andrea J Vet Intern Med Consensus Statement BACKGROUND: Thoracolumbar intervertebral disc extrusion (TL‐IVDE) is the most common cause of acute paraparesis and paraplegia in dogs; however, guidelines on management of the condition are lacking. OBJECTIVES: To summarize the current literature as it relates to diagnosis and management of acute TL‐IVDE in dogs, and to formulate clinically relevant evidence‐based recommendations. ANIMALS: None. METHODS: A panel of 8 experts was convened to assess and summarize evidence from the peer‐reviewed literature in order to develop consensus clinical recommendations. Level of evidence available to support each recommendation was assessed and reported. RESULTS: The majority of available literature described observational studies. Most recommendations made by the panel were supported by a low or moderate level of evidence, and several areas of high need for further study were identified. These include better understanding of the ideal timing for surgical decompression, expected surgical vs medical outcomes for more mildly affected dogs, impact of durotomy on locomotor outcome and development of progressive myelomalacia, and refining of postoperative care, and genetic and preventative care studies. CONCLUSIONS AND CLINICAL IMPORTANCE: Future efforts should build on current recommendations by conducting prospective studies and randomized controlled trials, where possible, to address identified gaps in knowledge and to develop cost effectiveness and number needed to treat studies supporting various aspects of diagnosis and treatment of TL‐IVDE. John Wiley & Sons, Inc. 2022-07-25 2022 /pmc/articles/PMC9511077/ /pubmed/35880267 http://dx.doi.org/10.1111/jvim.16480 Text en © 2022 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals LLC on behalf of American College of Veterinary Internal Medicine. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Consensus Statement
Olby, Natasha J.
Moore, Sarah A.
Brisson, Brigitte
Fenn, Joe
Flegel, Thomas
Kortz, Gregg
Lewis, Melissa
Tipold, Andrea
ACVIM consensus statement on diagnosis and management of acute canine thoracolumbar intervertebral disc extrusion
title ACVIM consensus statement on diagnosis and management of acute canine thoracolumbar intervertebral disc extrusion
title_full ACVIM consensus statement on diagnosis and management of acute canine thoracolumbar intervertebral disc extrusion
title_fullStr ACVIM consensus statement on diagnosis and management of acute canine thoracolumbar intervertebral disc extrusion
title_full_unstemmed ACVIM consensus statement on diagnosis and management of acute canine thoracolumbar intervertebral disc extrusion
title_short ACVIM consensus statement on diagnosis and management of acute canine thoracolumbar intervertebral disc extrusion
title_sort acvim consensus statement on diagnosis and management of acute canine thoracolumbar intervertebral disc extrusion
topic Consensus Statement
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9511077/
https://www.ncbi.nlm.nih.gov/pubmed/35880267
http://dx.doi.org/10.1111/jvim.16480
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