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Tea consumption affects the absorption of levothyroxine
Levothyroxine (LT4) is a convenient treatment for hypothyroidism. Coffee, however, prevents the body from efficaciously absorbing LT4. It is unknown whether the intake of tea interferes with LT4 absorption. Thirty-seven hypothyroidism patients with the following types of consumption were recruited:...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9511168/ https://www.ncbi.nlm.nih.gov/pubmed/36171905 http://dx.doi.org/10.3389/fendo.2022.943775 |
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author | Lai, Ying-Wen Huang, Shih-Ming |
author_facet | Lai, Ying-Wen Huang, Shih-Ming |
author_sort | Lai, Ying-Wen |
collection | PubMed |
description | Levothyroxine (LT4) is a convenient treatment for hypothyroidism. Coffee, however, prevents the body from efficaciously absorbing LT4. It is unknown whether the intake of tea interferes with LT4 absorption. Thirty-seven hypothyroidism patients with the following types of consumption were recruited: 1) only tea, 2) tea and coffee, and 3) only coffee. The concentrations of thyroid-stimulating hormone (TSH), triiodothyronine (T3), and thyroxine (T4) were recorded before and 3 months after changing the consumption. The patients had reductions in the concentration of TSH to varying degrees after 3 months (p < 0.001 or p < 0.05). The natural logarithms of the differences between the concentrations of TSH before and after the change in the consumption (Δln-TSH) of tea and coffee, only coffee, and only tea were 1.94, 2.00, and 2.18, respectively. Long-term consumption of tea, like coffee, interfered with the absorption of LT4. We believe that avoiding tea when taking LT4 will reduce malabsorption. |
format | Online Article Text |
id | pubmed-9511168 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-95111682022-09-27 Tea consumption affects the absorption of levothyroxine Lai, Ying-Wen Huang, Shih-Ming Front Endocrinol (Lausanne) Endocrinology Levothyroxine (LT4) is a convenient treatment for hypothyroidism. Coffee, however, prevents the body from efficaciously absorbing LT4. It is unknown whether the intake of tea interferes with LT4 absorption. Thirty-seven hypothyroidism patients with the following types of consumption were recruited: 1) only tea, 2) tea and coffee, and 3) only coffee. The concentrations of thyroid-stimulating hormone (TSH), triiodothyronine (T3), and thyroxine (T4) were recorded before and 3 months after changing the consumption. The patients had reductions in the concentration of TSH to varying degrees after 3 months (p < 0.001 or p < 0.05). The natural logarithms of the differences between the concentrations of TSH before and after the change in the consumption (Δln-TSH) of tea and coffee, only coffee, and only tea were 1.94, 2.00, and 2.18, respectively. Long-term consumption of tea, like coffee, interfered with the absorption of LT4. We believe that avoiding tea when taking LT4 will reduce malabsorption. Frontiers Media S.A. 2022-09-12 /pmc/articles/PMC9511168/ /pubmed/36171905 http://dx.doi.org/10.3389/fendo.2022.943775 Text en Copyright © 2022 Lai and Huang https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Endocrinology Lai, Ying-Wen Huang, Shih-Ming Tea consumption affects the absorption of levothyroxine |
title | Tea consumption affects the absorption of levothyroxine |
title_full | Tea consumption affects the absorption of levothyroxine |
title_fullStr | Tea consumption affects the absorption of levothyroxine |
title_full_unstemmed | Tea consumption affects the absorption of levothyroxine |
title_short | Tea consumption affects the absorption of levothyroxine |
title_sort | tea consumption affects the absorption of levothyroxine |
topic | Endocrinology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9511168/ https://www.ncbi.nlm.nih.gov/pubmed/36171905 http://dx.doi.org/10.3389/fendo.2022.943775 |
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