A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia

[Image: see text] Inflammatory responses are important in cancer, particularly in the context of monocyte-rich aggressive myeloid neoplasm. We developed a label-free cellular phenotypic drug discovery assay to identify anti-inflammatory drugs in human monocytes derived from acute myeloid leukemia (A...

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Detalles Bibliográficos
Autores principales: Marín-Rubio, José Luis, Peltier-Heap, Rachel E., Dueñas, Maria Emilia, Heunis, Tiaan, Dannoura, Abeer, Inns, Joseph, Scott, Jonathan, Simpson, A. John, Blair, Helen J., Heidenreich, Olaf, Allan, James M., Watt, Jessica E., Martin, Mathew P., Saxty, Barbara, Trost, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9511480/
https://www.ncbi.nlm.nih.gov/pubmed/36094045
http://dx.doi.org/10.1021/acs.jmedchem.2c00671

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