Cationic antimicrobial peptide NRC-03 induces oral squamous cell carcinoma cell apoptosis via CypD-mPTP axis-mediated mitochondrial oxidative stress

Pleurocidin-family cationic antimicrobial peptide NRC-03 exhibits potent and selective cytotoxicity towards cancer cells. However, the anticancer effect of NRC-03 in oral squamous cell carcinoma (OSCC) and the molecular mechanism of NRC-03 induced cancer cell death is still unclear. This study focus...

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Detalles Bibliográficos
Autores principales: Hou, Dan, Hu, Fengjun, Mao, Yixin, Yan, Liang, Zhang, Yuhui, Zheng, Zhichao, Wu, Antong, Forouzanfar, Tymour, Pathak, Janak L., Wu, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9511698/
https://www.ncbi.nlm.nih.gov/pubmed/35660629
http://dx.doi.org/10.1016/j.redox.2022.102355

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