Cryoprecipitate transfusion in trauma patients attenuates hyperfibrinolysis and restores normal clot structure and stability: Results from a laboratory sub-study of the FEISTY trial

BACKGROUND: Fibrinogen is the first coagulation protein to reach critical levels during traumatic haemorrhage. This laboratory study compares paired plasma samples pre- and post-fibrinogen replacement from the Fibrinogen Early In Severe Trauma studY (FEISTY; NCT02745041). FEISTY is the first randomi...

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Detalles Bibliográficos
Autores principales: Morrow, Gael B., Feller, Timea, McQuilten, Zoe, Wake, Elizabeth, Ariëns, Robert A. S., Winearls, James, Mutch, Nicola J., Laffan, Mike A., Curry, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9511733/
https://www.ncbi.nlm.nih.gov/pubmed/36163263
http://dx.doi.org/10.1186/s13054-022-04167-x

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