AADAC protects colorectal cancer liver colonization from ferroptosis through SLC7A11-dependent inhibition of lipid peroxidation

BACKGROUND: Oxidative stress is a highly active metabolic process in the liver, that poses great threats to disseminated tumor cells during their colonization. Here, we aimed to investigate how colorectal cancer (CRC) cells overcome lipid peroxidation to sustain their metastatic colonization in the...

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Detalles Bibliográficos
Autores principales: Sun, Rongquan, Lin, Zhifei, Wang, Xiangyu, Liu, Lu, Huo, Meisi, Zhang, Rui, Lin, Jing, Xiao, Chao, Li, Yitong, Zhu, Wenwei, Lu, Lu, Zhang, Jubo, Chen, Jinhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9511737/
https://www.ncbi.nlm.nih.gov/pubmed/36163032
http://dx.doi.org/10.1186/s13046-022-02493-0

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