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Targeting the MALAT1 gene with the CRISPR/Cas9 technique in prostate cancer

BACKGROUND: The MALAT1 lncRNA acts as an oncogene in Prostate cancer (PC); thus, it can be severe as a cancer biomarker. METHODS: Using bioinformatics datasets including (HTSeq-Counts, GDC, and TCGA) 5501 gene expression profiling specimens were gathered. Then, expression profiles and sample surviva...

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Detalles Bibliográficos
Autores principales: Ahmadi-Balootaki, Soraya, Doosti, Abbas, Jafarinia, Mojtaba, Goodarzi, Hamed Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9511773/
https://www.ncbi.nlm.nih.gov/pubmed/36163080
http://dx.doi.org/10.1186/s41021-022-00252-3