Cargando…

Discrepancies between tumor genomic profiling and germline genetic testing

BACKGROUND: Tumor genomic profiling (TGP) often incidentally identifies germline pathogenic variants (PVs) associated with cancer predisposition syndromes. Methods used by somatic testing laboratories, including germline analysis, differ from designated germline laboratories that have optimized the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pauley, K., Koptiuch, C., Greenberg, S., Kohlmann, W., Jeter, J., Colonna, S., Werner, T., Kinsey, C., Gilcrease, G., Weis, J., Whisenant, J., Florou, V., Garrido-Laguna, I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9511791/ https://www.ncbi.nlm.nih.gov/pubmed/35780590 http://dx.doi.org/10.1016/j.esmoop.2022.100526

Ejemplares similares

Considerations for Germline Testing in Melanoma: Updates in Behavioral Change and Pancreatic Surveillance for Carriers of CDKN2A Pathogenic Variants
por: Pauley, Kristen, et al.
Publicado: (2022)

Survival of patients with metastatic HER2 positive gastro-oesophageal cancer treated with second-line chemotherapy plus trastuzumab or ramucirumab after progression on front-line chemotherapy plus trastuzumab
por: Nevala-Plagemann, Christopher, et al.
Publicado: (2019)

Mainstreaming germline genetic testing for patients with pancreatic cancer increases uptake
por: Ramsey, Mitchell L., et al.
Publicado: (2022)

Considerations for immunotherapy in patients with cancer and comorbid immune dysfunction
por: Florou, Vaia, et al.
Publicado: (2021)

Treatment outcomes in recurrent versus de novo metastatic pancreatic adenocarcinoma: a real world study
por: Miotke, Laura, et al.
Publicado: (2022)

Germline testing and genetic counselling in prostate cancer
por: Russo, Jessica, et al.
Publicado: (2022)

Gene expression profiling of U2AF2 dependent RNA-protein interactions during CD4 + T cell activation
por: Whisenant, Thomas C
Publicado: (2016)

Prioritization of patients for germline testing based on tumor profiling of hematopoietic malignancies
por: Godley, Lucy A.
Publicado: (2023)

Discrepancies in the bilateral intradermal test and serum tests in atopic horses
por: van Damme, Catharina M. M., et al.
Publicado: (2020)

Potential pathogenic germline variant reporting from tumor comprehensive genomic profiling complements classic approaches to germline testing
por: Tung, Nadine, et al.
Publicado: (2023)

Germline genetic testing in prostate cancer – further enrichment in variant histologies?
por: Markowski, Mark C., et al.
Publicado: (2018)

Characterization of Pseudomonas aeruginosa with discrepant carbapenem susceptibility profile
por: Pragasam, Agila K., et al.
Publicado: (2016)

Non-Melanoma Skin Cancers and Other Cutaneous Manifestations in Bone Marrow Failure Syndromes and Rare DNA Repair Disorders
por: Vagher, Jennie, et al.
Publicado: (2022)

Repeat HIV testing of individuals with discrepant HIV self-test results in Central Uganda
por: Kisa, Rose, et al.
Publicado: (2019)

A prenatal case with discrepant findings between non-invasive prenatal testing and fetal genetic testings
por: Pan, Qiong, et al.
Publicado: (2014)

Transcriptome Profiling in Rat Inbred Strains and Experimental Cross Reveals Discrepant Genetic Architecture of Genome-Wide Gene Expression
por: Kaisaki, Pamela J., et al.
Publicado: (2016)

Does Transfusion of Red Blood Cells Impact Germline Genetic Test Results?
por: DiGuardo, Maggie A., et al.
Publicado: (2020)

Evaluation of Germline Genetic Testing Criteria in a Hospital-Based Series of Women With Breast Cancer
por: Yadav, Siddhartha, et al.
Publicado: (2020)

Eligibility, uptake and response to germline genetic testing in women with DCIS
por: Turza, Lauren, et al.
Publicado: (2022)

Germline variant testing in serrated polyposis syndrome
por: Murphy, Aisling, et al.
Publicado: (2022)

N of 1 case reports of exceptional responders accrued from pancreatic cancer patients enrolled in first-in-man studies from 2002 through 2012
por: Garrido-Laguna, Ignacio, et al.
Publicado: (2015)

Geometric Discrepancy
por: Matousek, Jiri
Publicado: (1999)

Splicing profile by capture RNA-seq identifies pathogenic germline variants in tumor suppressor genes
por: Landrith, Tyler, et al.
Publicado: (2020)

Genetic Counseling and Germline Testing in the Era of Tumor Sequencing: A Cohort Study
por: Klek, Stefan, et al.
Publicado: (2020)

Discrepancy in Vancomycin AUC/MIC Ratio Targeted Attainment Based upon the Susceptibility Testing in Staphylococcus aureus
por: Eum, Seenae, et al.
Publicado: (2016)

Sebaceous tumours: a prototypical class of skin tumour for universal germline genetic testing
por: Gallon, R., et al.
Publicado: (2021)

Benefit of adjuvant chemotherapy based on lymph node involvement for oesophageal cancer following trimodality therapy
por: Nevala-Plagemann, Christopher, et al.
Publicado: (2018)

A phase I open-label study of the safety and efficacy of apatinib (rivoceranib) administered to patients with advanced malignancies to improve sensitivity to pembrolizumab in the second- or later-line setting (APPEASE)
por: Gumbleton, Matthew, et al.
Publicado: (2023)

Discrepancies in the calibration of reaction rate analysers
por: Legg, E. F., et al.
Publicado: (1980)

The ethnic profile of patients with birthmarks reveals interaction of germline and postzygotic genetics
por: Polubothu, S., et al.
Publicado: (2017)

Discrepancies of SARS-CoV-2 testing results among patients with total laryngectomy
por: Fabbris, C., et al.
Publicado: (2021)

Integration of Universal Germline Genetic Testing for All New Breast Cancer Patients
por: Culver, Julie O., et al.
Publicado: (2022)

Clinical Utility of Universal Germline Genetic Testing for Patients With Breast Cancer
por: Whitworth, Pat W., et al.
Publicado: (2022)

UK recommendations for SDHA germline genetic testing and surveillance in clinical practice
por: Hanson, Helen, et al.
Publicado: (2023)

Internet-Based Germline Genetic Testing for Men With Metastatic Prostate Cancer
por: Cheng, Heather H., et al.
Publicado: (2023)

Payer reimbursement practices and incentives for improving interpretation of germline genetic testing
por: Deverka, Patricia, et al.
Publicado: (2023)

The Kardashian index: a measure of discrepant social media profile for scientists
por: Hall, Neil
Publicado: (2014)

Peritoneal Equilibration Test in Costa Rica: Discrepancies from Other Populations
por: Avellan-Boza, Marta, et al.
Publicado: (2014)

Sequences, discrepancies and applications
por: Drmota, Michael, et al.
Publicado: (1997)

Discrepancies as to the Number of the Insured
Publicado: (1915)

Cannot write session to /tmp/vufind_sessions/sess_s7l5dujor42dv10t21sjjpo5oa