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Dual drug delivery platforms for bone tissue engineering
The dual delivery platforms used in bone tissue engineering provide supplementary bioactive compounds that include distinct medicines and growth factors thereby aiding enhanced bone regeneration. The delivery of these compounds can be adjusted for a short or prolonged time based on the requirement b...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9511792/ https://www.ncbi.nlm.nih.gov/pubmed/36172012 http://dx.doi.org/10.3389/fbioe.2022.969843 |
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author | V. K., Anupama Devi Ray, Sarbajit Arora, Udita Mitra, Sunrito Sionkowska, Alina Jaiswal, Amit Kumar |
author_facet | V. K., Anupama Devi Ray, Sarbajit Arora, Udita Mitra, Sunrito Sionkowska, Alina Jaiswal, Amit Kumar |
author_sort | V. K., Anupama Devi |
collection | PubMed |
description | The dual delivery platforms used in bone tissue engineering provide supplementary bioactive compounds that include distinct medicines and growth factors thereby aiding enhanced bone regeneration. The delivery of these compounds can be adjusted for a short or prolonged time based on the requirement by altering various parameters of the carrier platform. The platforms thus used are fabricated to mimic the niche of the bone microenvironment, either in the form of porous 3D structures, microspheres, or films. Thus, this review article focuses on the concept of dual drug delivery platform and its importance, classification of various platforms for dual drug delivery specific to bone tissue engineering, and finally highlights the foresight into the future direction of these techniques for better clinical applications. |
format | Online Article Text |
id | pubmed-9511792 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-95117922022-09-27 Dual drug delivery platforms for bone tissue engineering V. K., Anupama Devi Ray, Sarbajit Arora, Udita Mitra, Sunrito Sionkowska, Alina Jaiswal, Amit Kumar Front Bioeng Biotechnol Bioengineering and Biotechnology The dual delivery platforms used in bone tissue engineering provide supplementary bioactive compounds that include distinct medicines and growth factors thereby aiding enhanced bone regeneration. The delivery of these compounds can be adjusted for a short or prolonged time based on the requirement by altering various parameters of the carrier platform. The platforms thus used are fabricated to mimic the niche of the bone microenvironment, either in the form of porous 3D structures, microspheres, or films. Thus, this review article focuses on the concept of dual drug delivery platform and its importance, classification of various platforms for dual drug delivery specific to bone tissue engineering, and finally highlights the foresight into the future direction of these techniques for better clinical applications. Frontiers Media S.A. 2022-09-12 /pmc/articles/PMC9511792/ /pubmed/36172012 http://dx.doi.org/10.3389/fbioe.2022.969843 Text en Copyright © 2022 V. K., Ray, Arora, Mitra, Sionkowska and Jaiswal. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Bioengineering and Biotechnology V. K., Anupama Devi Ray, Sarbajit Arora, Udita Mitra, Sunrito Sionkowska, Alina Jaiswal, Amit Kumar Dual drug delivery platforms for bone tissue engineering |
title | Dual drug delivery platforms for bone tissue engineering |
title_full | Dual drug delivery platforms for bone tissue engineering |
title_fullStr | Dual drug delivery platforms for bone tissue engineering |
title_full_unstemmed | Dual drug delivery platforms for bone tissue engineering |
title_short | Dual drug delivery platforms for bone tissue engineering |
title_sort | dual drug delivery platforms for bone tissue engineering |
topic | Bioengineering and Biotechnology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9511792/ https://www.ncbi.nlm.nih.gov/pubmed/36172012 http://dx.doi.org/10.3389/fbioe.2022.969843 |
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