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Dual drug delivery platforms for bone tissue engineering

The dual delivery platforms used in bone tissue engineering provide supplementary bioactive compounds that include distinct medicines and growth factors thereby aiding enhanced bone regeneration. The delivery of these compounds can be adjusted for a short or prolonged time based on the requirement b...

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Autores principales: V. K., Anupama Devi, Ray, Sarbajit, Arora, Udita, Mitra, Sunrito, Sionkowska, Alina, Jaiswal, Amit Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9511792/
https://www.ncbi.nlm.nih.gov/pubmed/36172012
http://dx.doi.org/10.3389/fbioe.2022.969843
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author V. K., Anupama Devi
Ray, Sarbajit
Arora, Udita
Mitra, Sunrito
Sionkowska, Alina
Jaiswal, Amit Kumar
author_facet V. K., Anupama Devi
Ray, Sarbajit
Arora, Udita
Mitra, Sunrito
Sionkowska, Alina
Jaiswal, Amit Kumar
author_sort V. K., Anupama Devi
collection PubMed
description The dual delivery platforms used in bone tissue engineering provide supplementary bioactive compounds that include distinct medicines and growth factors thereby aiding enhanced bone regeneration. The delivery of these compounds can be adjusted for a short or prolonged time based on the requirement by altering various parameters of the carrier platform. The platforms thus used are fabricated to mimic the niche of the bone microenvironment, either in the form of porous 3D structures, microspheres, or films. Thus, this review article focuses on the concept of dual drug delivery platform and its importance, classification of various platforms for dual drug delivery specific to bone tissue engineering, and finally highlights the foresight into the future direction of these techniques for better clinical applications.
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spelling pubmed-95117922022-09-27 Dual drug delivery platforms for bone tissue engineering V. K., Anupama Devi Ray, Sarbajit Arora, Udita Mitra, Sunrito Sionkowska, Alina Jaiswal, Amit Kumar Front Bioeng Biotechnol Bioengineering and Biotechnology The dual delivery platforms used in bone tissue engineering provide supplementary bioactive compounds that include distinct medicines and growth factors thereby aiding enhanced bone regeneration. The delivery of these compounds can be adjusted for a short or prolonged time based on the requirement by altering various parameters of the carrier platform. The platforms thus used are fabricated to mimic the niche of the bone microenvironment, either in the form of porous 3D structures, microspheres, or films. Thus, this review article focuses on the concept of dual drug delivery platform and its importance, classification of various platforms for dual drug delivery specific to bone tissue engineering, and finally highlights the foresight into the future direction of these techniques for better clinical applications. Frontiers Media S.A. 2022-09-12 /pmc/articles/PMC9511792/ /pubmed/36172012 http://dx.doi.org/10.3389/fbioe.2022.969843 Text en Copyright © 2022 V. K., Ray, Arora, Mitra, Sionkowska and Jaiswal. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Bioengineering and Biotechnology
V. K., Anupama Devi
Ray, Sarbajit
Arora, Udita
Mitra, Sunrito
Sionkowska, Alina
Jaiswal, Amit Kumar
Dual drug delivery platforms for bone tissue engineering
title Dual drug delivery platforms for bone tissue engineering
title_full Dual drug delivery platforms for bone tissue engineering
title_fullStr Dual drug delivery platforms for bone tissue engineering
title_full_unstemmed Dual drug delivery platforms for bone tissue engineering
title_short Dual drug delivery platforms for bone tissue engineering
title_sort dual drug delivery platforms for bone tissue engineering
topic Bioengineering and Biotechnology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9511792/
https://www.ncbi.nlm.nih.gov/pubmed/36172012
http://dx.doi.org/10.3389/fbioe.2022.969843
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