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Persistent EGFR/K-RAS/SIAH pathway activation drives chemo-resistance and early tumor relapse in triple-negative breast cancer

Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subtype. It disproportionately affects BRCA mutation carriers and young women, especially African American (AA) women. Chemoresistant TNBC is a heterogeneous and molecularly unstable disease that challenges our ability to appl...

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Detalles Bibliográficos
Autores principales: Tang, Amy H., Hoefer, Richard A., Guye, Mary L., Bear, Harry D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: OAE Publishing Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9511813/
https://www.ncbi.nlm.nih.gov/pubmed/36176751
http://dx.doi.org/10.20517/cdr.2022.31

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