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Computational Modeling of RNA Aptamers: Structure Prediction of the Apo State

[Image: see text] RNA aptamers are single-stranded oligonucleotides that bind to specific molecular targets with high affinity and specificity. To design aptamers for new applications, it is critical to understand the ligand binding mechanism in terms of the structure and dynamics of the ligand-boun...

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Detalles Bibliográficos
Autores principales: Yan, Shuting, Ilgu, Muslum, Nilsen-Hamilton, Marit, Lamm, Monica H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9512008/
https://www.ncbi.nlm.nih.gov/pubmed/36097649
http://dx.doi.org/10.1021/acs.jpcb.2c04649