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Computational Modeling of RNA Aptamers: Structure Prediction of the Apo State
[Image: see text] RNA aptamers are single-stranded oligonucleotides that bind to specific molecular targets with high affinity and specificity. To design aptamers for new applications, it is critical to understand the ligand binding mechanism in terms of the structure and dynamics of the ligand-boun...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9512008/ https://www.ncbi.nlm.nih.gov/pubmed/36097649 http://dx.doi.org/10.1021/acs.jpcb.2c04649 |