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NOT ALL CELL-FREE MITOCHONDRIAL DNA IS EQUAL IN TRAUMA PATIENTS

Mitochondrial DNA (mtDNA) acts as a proinflammatory damage-associated molecular pattern that stimulates innate immune activation via Toll-like receptor 9, similarly to bacterial DNA. A number of clinical studies have measured elevated cell-free mtDNA in the plasma of trauma patients, thought to orig...

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Detalles Bibliográficos
Autores principales:	Briggs, Gabrielle D., Gelzinnis, Scott, Meakes, Simone, King, Kate L., Balogh, Zsolt J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2022
Materias:	Clinical Science Aspects
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9512242/ https://www.ncbi.nlm.nih.gov/pubmed/36125357 http://dx.doi.org/10.1097/SHK.0000000000001969

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