Cargando…

Progress and Challenges of Anti-VEGF Agents and Their Sustained-Release Strategies for Retinal Angiogenesis

Currently, the treatment for ocular neovascular diseases, including diabetic macular edema (DME) and age-related macular degeneration (AMD), mainly involves repeated intravitreal injection of anti-vascular endothelial growth factor (VEGF) drugs. Although it can preserve vision, repeated injections a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Manhong, Fan, Ruiyan, Fan, Xiaoe, Shao, Yan, Li, Xiaorong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9512290/ https://www.ncbi.nlm.nih.gov/pubmed/36172053 http://dx.doi.org/10.2147/DDDT.S383101

Ejemplares similares

Steroid Drugs as an Adjunct for Reducing the Incidence of Proliferative Vitreoretinopathy after Rhegmatogenous Retinal Detachment Surgery: A Meta-Analysis of Randomized Controlled Studies
por: Xu, Manhong, et al.
Publicado: (2023)

Anti-VEGF Agents for Ocular Angiogenesis and Vascular Permeability
por: Kimoto, Kenichi, et al.
Publicado: (2012)

Effects of anti-VEGF agents on rat retinal Müller glial cells
por: Guo, Bin, et al.
Publicado: (2010)

Biological drug therapy for ocular angiogenesis: Anti‐VEGF agents and novel strategies based on nanotechnology
por: Formica, María L., et al.
Publicado: (2021)

Sustained Release of VEGF to Promote Angiogenesis and Osteointegration of Three-Dimensional Printed Biomimetic Titanium Alloy Implants
por: Li, Youbin, et al.
Publicado: (2021)

Use of biomaterials for sustained delivery of anti-VEGF to treat retinal diseases
por: Seah, Ivan, et al.
Publicado: (2020)

An experimental study of VEGF induced changes in vasoactivity in pig retinal arterioles and the influence of an anti-VEGF agent
por: Su, Er-Ning, et al.
Publicado: (2012)

Correction: Use of biomaterials for sustained delivery for anti-VEGF to treat retinal diseases
por: Seah, Ivan, et al.
Publicado: (2020)

Coaxial Electrospray of Ranibizumab-Loaded Microparticles for Sustained Release of Anti-VEGF Therapies
por: Zhang, Leilei, et al.
Publicado: (2015)

Hollow Microcapsules as Periocular Drug Depot for Sustained Release of Anti-VEGF Protein
por: Radhakrishnan, Krishna, et al.
Publicado: (2019)

Thermo-responsive hydrogel as an anti-VEGF drug delivery system to inhibit retinal angiogenesis in Rex rabbits
por: Hu, Chao-Chien, et al.
Publicado: (2019)

Receptors that bind to PEDF and their therapeutic roles in retinal diseases
por: Xu, Manhong, et al.
Publicado: (2023)

Alginate hydrogels allow for bioactive and sustained release of VEGF-C and VEGF-D for lymphangiogenic therapeutic applications
por: Campbell, Kevin T., et al.
Publicado: (2017)

KLF4 Promotes Angiogenesis by Activating VEGF Signaling in Human Retinal Microvascular Endothelial Cells
por: Wang, Yinan, et al.
Publicado: (2015)

Human embryonic stem cell-derived extracellular vesicles alleviate retinal degeneration by upregulating Oct4 to promote retinal Müller cell retrodifferentiation via HSP90
por: Ke, Yifeng, et al.
Publicado: (2021)

Correction to: Human embryonic stem cell-derived extracellular vesicles alleviate retinal degeneration by upregulating Oct4 to promote retinal Müller cell retrodifferentiation via HSP90
por: Ke, Yifeng, et al.
Publicado: (2021)

Gastric Cancer and Angiogenesis: Is VEGF a Useful Biomarker to Assess Progression and Remission?
por: Macedo, Filipa, et al.
Publicado: (2017)

BICC1 drives pancreatic cancer progression by inducing VEGF-independent angiogenesis
por: Huang, Chongbiao, et al.
Publicado: (2023)

Platelet releasate promotes breast cancer growth and angiogenesis via VEGF–integrin cooperative signalling
por: Jiang, Lei, et al.
Publicado: (2017)

Visual and anatomic outcomes of sustained single agent anti-VEGF treatment versus double anti-VEGF switching in the treatment of persistent diabetic macular edema
por: Sorour, Osama A., et al.
Publicado: (2020)

VEGF tips its hand in angiogenesis
por: Short, Ben
Publicado: (2015)

Enhanced Vascularization in Hybrid PCL/Gelatin Fibrous Scaffolds with Sustained Release of VEGF
por: Wang, Kai, et al.
Publicado: (2015)

VEGF Spliced Variants: Possible Role of Anti-Angiogenesis Therapy
por: Hilmi, Caroline, et al.
Publicado: (2012)

Mechanism of action of platinum nanoparticles implying from antioxidant to metabolic programming in light-induced retinal degeneration model
por: Su, Lin, et al.
Publicado: (2023)

Regulation of Pathologic Retinal Angiogenesis in Mice and Inhibition of VEGF-VEGFR2 Binding by Soluble Heparan Sulfate
por: Nishiguchi, Koji M., et al.
Publicado: (2010)

Retinal function determined by flicker ERGs before and soon after intravitreal injection of anti-VEGF agents
por: Terauchi, Gaku, et al.
Publicado: (2019)

Retinal layers changes in patients with age-related macular degeneration treated with intravitreal anti-VEGF agents
por: Zhou, Dan, et al.
Publicado: (2023)

Visfatin Increases VEGF-Dependent Angiogenesis of Endothelial Progenitor Cells during Osteoarthritis Progression
por: Tsai, Chun-Hao, et al.
Publicado: (2020)

Inhibition of KCTD10 Affects Diabetic Retinopathy Progression by Reducing VEGF and Affecting Angiogenesis
por: Feng, Yun, et al.
Publicado: (2022)

Preparation and Biocompatibility of Core-Shell Microspheres for Sequential, Sustained Release of BMP-2 and VEGF
por: Liu, Zheng, et al.
Publicado: (2022)

Aloe-emodin suppresses hypoxia-induced retinal angiogenesis via inhibition of HIF-1α/VEGF pathway
por: Wu, Jianming, et al.
Publicado: (2016)

Antibody Targeting of Cathepsin S Inhibits Angiogenesis and Synergistically Enhances Anti-VEGF
por: Ward, Claire, et al.
Publicado: (2010)

Regulation of Osteogenesis-Angiogenesis Coupling by HIFs and VEGF
por: Schipani, Ernestina, et al.
Publicado: (2009)

The role of VEGF receptors in angiogenesis; complex partnerships
por: Cébe-Suarez, S., et al.
Publicado: (2006)

Biomarkers of angiogenesis and their role in the development of VEGF inhibitors
por: Murukesh, N, et al.
Publicado: (2010)

VEGF stimulated the angiogenesis by promoting the mitochondrial functions
por: Guo, Dongqing, et al.
Publicado: (2017)

SALL4 promotes angiogenesis in gastric cancer by regulating VEGF expression and targeting SALL4/VEGF pathway inhibits cancer progression
por: Abouelnazar, Fatma A., et al.
Publicado: (2023)

Sustained delivery of anti-VEGF from injectable hydrogel systems provides a prolonged decrease of endothelial cell proliferation and angiogenesis in vitro
por: Fletcher, Nathan A., et al.
Publicado: (2018)

Anti-VEGF Agents and Glaucoma Filtering Surgery
por: Daneshvar, Ramin
Publicado: (2013)

Use of Anti-VEGF Agents in Glaucoma Surgery
por: Slabaugh, Mark, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_tdo90vdovnn9903bcvgq7nm9dg