Fip1 is a multivalent interaction scaffold for processing factors in human mRNA 3′ end biogenesis

3′ end formation of most eukaryotic mRNAs is dependent on the assembly of a ~1.5 MDa multiprotein complex, that catalyzes the coupled reaction of pre-mRNA cleavage and polyadenylation. In mammals, the cleavage and polyadenylation specificity factor (CPSF) constitutes the core of the 3′ end processin...

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Detalles Bibliográficos
Autores principales: Muckenfuss, Lena Maria, Migenda Herranz, Anabel Carmen, Boneberg, Franziska Maria, Clerici, Marcello, Jinek, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9512404/
https://www.ncbi.nlm.nih.gov/pubmed/36073787
http://dx.doi.org/10.7554/eLife.80332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9512404/
https://www.ncbi.nlm.nih.gov/pubmed/36073787
http://dx.doi.org/10.7554/eLife.80332

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