Cargando…

Loss of heat shock factor 1 promotes hepatic stellate cell activation and drives liver fibrosis

Liver fibrosis is an aberrant wound healing response that results from chronic injury and is mediated by hepatocellular death and activation of hepatic stellate cells (HSCs). While induction of oxidative stress is well established in fibrotic livers, there is limited information on stress‐mediated m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Choudhury, Asmita, Ratna, Anuradha, Lim, Arlene, Sebastian, Rebecca M., Moore, Christopher L., Filliol, Aveline A., Bledsoe, Jacob, Dai, Chengkai, Schwabe, Robert F., Shoulders, Matthew D., Mandrekar, Pranoti
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9512451/ https://www.ncbi.nlm.nih.gov/pubmed/35945902 http://dx.doi.org/10.1002/hep4.2058

Ejemplares similares

FoxM1 Induces CCl2 Secretion From Hepatocytes Triggering Hepatic Inflammation, Injury, Fibrosis, and Liver Cancer
por: Filliol, Aveline, et al.
Publicado: (2020)

Alcohol and Cancer: Mechanisms and Therapies
por: Ratna, Anuradha, et al.
Publicado: (2017)

Myeloid Endoplasmic Reticulum Resident Chaperone GP96 Facilitates Inflammation and Steatosis in Alcohol‐Associated Liver Disease
por: Ratna, Anuradha, et al.
Publicado: (2021)

A Therapeutic Silencing RNA Targeting Hepatocyte TAZ Prevents and Reverses Fibrosis in Nonalcoholic Steatohepatitis in Mice
por: Wang, Xiaobo, et al.
Publicado: (2019)

Advancing hepatology research: Excellence in open access
por: Mandrekar, Pranoti
Publicado: (2017)

Targeting Epigenetic Mechanisms to Alleviate Alcoholic Steatosis
por: Mandrekar, Pranoti
Publicado: (2020)

Oxidative Stress and Inflammation: Essential Partners in Alcoholic Liver Disease
por: Ambade, Aditya, et al.
Publicado: (2012)

Focus On: Alcohol and the Liver
por: Szabo, Gyongyi, et al.
Publicado: (2010)

Macrophages and Alcohol-Related Liver Inflammation
por: Ju, Cynthia, et al.
Publicado: (2015)

Periostin and mesothelin: Potential predictors of malignant progression in intrahepatic cholangiocarcinoma
por: Mandrekar, Pranoti, et al.
Publicado: (2018)

SUMOylation and the HSF1-Regulated Chaperone Network Converge to Promote Proteostasis in Response to Heat Shock
por: Liebelt, Frauke, et al.
Publicado: (2019)

Sexual Dimorphism in Alcohol Induced Adipose Inflammation Relates to Liver Injury
por: Fulham, Melissa A., et al.
Publicado: (2016)

Heat shock factor 1 is a direct anti-amyloid factor: connecting neurodegeneration and uncontrolled growth
por: Tang, Zijian, et al.
Publicado: (2021)

Toll-Like Receptors in the Pathogenesis of Alcoholic Liver Disease
por: Petrasek, Jan, et al.
Publicado: (2010)

Characterizing the Altered Cellular Proteome Induced by the Stress-Independent Activation of Heat Shock Factor 1
por: Ryno, Lisa M., et al.
Publicado: (2014)

Heat shock factor 1 (HSF1) specifically potentiates c-MYC-mediated transcription independently of the canonical heat shock response
por: Xu, Meng, et al.
Publicado: (2023)

Endogenous IL-33 has no effect on the progression of fibrosis during experimental steatohepatitis
por: Vasseur, Philippe, et al.
Publicado: (2017)

Heat Shock Factor 1 Drives Intergenic Association of Its Target Gene Loci upon Heat Shock
por: Chowdhary, Surabhi, et al.
Publicado: (2019)

Fate-tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its etiology
por: Mederacke, Ingmar, et al.
Publicado: (2013)

SIRT6 Protects Against Liver Fibrosis by Deacetylation and Suppression of SMAD3 in Hepatic Stellate Cells
por: Zhong, Xiaolin, et al.
Publicado: (2020)

Pharmacological Intervention in Hepatic Stellate Cell Activation and Hepatic Fibrosis
por: Schon, Hans-Theo, et al.
Publicado: (2016)

Heat shock drives genomic instability and phenotypic variations in yeast
por: Shen, Li, et al.
Publicado: (2020)

Toll‐like receptor‐2 exacerbates murine acute viral hepatitis
por: Bleau, Christian, et al.
Publicado: (2016)

Editorial: Macrophages in Liver Disease
por: Bansal, Ruchi, et al.
Publicado: (2020)

Hepatocyte mitochondria-derived danger signals directly activate hepatic stellate cells and drive progression of liver fibrosis
por: An, Ping, et al.
Publicado: (2020)

Liver fibrosis is driven by protease‐activated receptor‐1 expressed by hepatic stellate cells in experimental chronic liver injury
por: Poole, Lauren G., et al.
Publicado: (2020)

Cellular Proteomes Drive Tissue-Specific Regulation of the Heat Shock Response
por: Ma, Jian, et al.
Publicado: (2017)

Investigating the role of heat shock protein 47 in fibrosis in Crohn’s disease
por: Kurumi, Hiroki, et al.
Publicado: (2022)

Editorial: Cell-to-cell communications in alcohol-associated, metabolic-related and viral liver diseases
por: Osna, Natalia A., et al.
Publicado: (2023)

Hepatic stellate cells and parasite-induced liver fibrosis
por: Anthony, Barrie, et al.
Publicado: (2010)

Metabolic Hallmarks of Hepatic Stellate Cells in Liver Fibrosis
por: Khomich, Olga, et al.
Publicado: (2019)

MIR21 Drives Resistance to Heat Shock Protein 90 Inhibition in Cholangiocarcinoma
por: Lampis, Andrea, et al.
Publicado: (2018)

Smoking-associated fibrosis and pulmonary asbestosis
por: Bledsoe, Jacob R, et al.
Publicado: (2014)

Cellular communication network factor 1‐stimulated liver macrophage efferocytosis drives hepatic stellate cell activation and liver fibrosis
por: Kim, Ki‐Hyun, et al.
Publicado: (2022)

Macrophage‐derived HMGB1 is dispensable for tissue fibrogenesis
por: Personnaz, Jean, et al.
Publicado: (2019)

Involvement of collagen-binding heat shock protein 47 in scleroderma-associated fibrosis
por: Chu, Haiyan, et al.
Publicado: (2015)

Geranylgeranylacetone attenuates hepatic fibrosis by increasing the expression of heat shock protein 70
por: HE, WEI, et al.
Publicado: (2015)

Cannabinoids Reduce Markers of Inflammation and Fibrosis in Pancreatic Stellate Cells
por: Michalski, Christoph W., et al.
Publicado: (2008)

Hepatic Stellate Cells and microRNAs in Pathogenesis of Liver Fibrosis
por: Kitano, Mio, et al.
Publicado: (2016)

Succinate as a Regulator of Hepatic Stellate Cells in Liver Fibrosis
por: Cho, Eun-Hee
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_pjaq0coakupscdb4lslgppavii