Molecular determinants of peri‐apical targeting of inositol 1,4,5‐trisphosphate receptor type 3 in cholangiocytes

Fluid and bicarbonate secretion is a principal function of cholangiocytes, and impaired secretion results in cholestasis. Cholangiocyte secretion depends on peri‐apical expression of the type 3 inositol trisphosphate receptor (ITPR3), and loss of this intracellular Ca(2+) release channel is a final...

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Detalles Bibliográficos
Autores principales: Rodrigues, Michele A., Gomes, Dawidson A., Fiorotto, Romina, Guerra, Mateus T., Weerachayaphorn, Jittima, Bo, Tao, Sessa, William C., Strazzabosco, Mario, Nathanson, Michael H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9512452/
https://www.ncbi.nlm.nih.gov/pubmed/35852334
http://dx.doi.org/10.1002/hep4.2042

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