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Mouse model of NASH that replicates key features of the human disease and progresses to fibrosis stage 3

Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease in the United States and the world; with no Food and Drug Administration–approved pharmacological treatment available, it remains an area of unmet medical need. In nonalcoholic steatohepatitis (NASH), the most important predic...

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Detalles Bibliográficos
Autores principales: St. Rose, Kristy, Yan, Jun, Xu, Fangxi, Williams, Jasmine, Dweck, Virginia, Saxena, Deepak, Schwabe, Robert F., Caviglia, Jorge Matias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9512466/
https://www.ncbi.nlm.nih.gov/pubmed/35923109
http://dx.doi.org/10.1002/hep4.2035