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Protein Tyrosine Phosphatase 1B Deficiency in Vascular Smooth Muscle Cells Promotes Perivascular Fibrosis following Arterial Injury

Background Smooth muscle cell (SMC) phenotype switching plays a central role during vascular remodeling. Growth factor receptors are negatively regulated by protein tyrosine phosphatases (PTPs), including its prototype PTP1B. Here, we examine how reduction of PTP1B in SMCs affects the vascular remo...

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Detalles Bibliográficos
Autores principales:	Gogiraju, Rajinikanth, Gachkar, Sogol, Velmeden, David, Bochenek, Magdalena L., Zifkos, Konstantinos, Hubert, Astrid, Münzel, Thomas, Offermanns, Stefan, Schäfer, Katrin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Georg Thieme Verlag KG 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9512587/ https://www.ncbi.nlm.nih.gov/pubmed/36075234 http://dx.doi.org/10.1055/s-0042-1755329

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