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An ex-vivo assessment of a new single probe triple modality (Trilogy) lithotripter

INTRODUCTION AND OBJECTIVES: This Swiss LithoClast(®) Trilogy lithotrite is a new lithotrite for percutaneous nephrolithotomy (PCNL). It has four modifiable settings; impact, frequency, ultrasound and suction. We aim to determine the optimal device settings for the fastest stone clearance. MATERIALS...

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Autores principales: O’Connor, Charles Joseph, Hogan, Donnacha, Yap, Lee Chien, Lyons, Louise, Hennessey, Derek Barry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9512712/
https://www.ncbi.nlm.nih.gov/pubmed/36001137
http://dx.doi.org/10.1007/s00345-022-04127-8
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author O’Connor, Charles Joseph
Hogan, Donnacha
Yap, Lee Chien
Lyons, Louise
Hennessey, Derek Barry
author_facet O’Connor, Charles Joseph
Hogan, Donnacha
Yap, Lee Chien
Lyons, Louise
Hennessey, Derek Barry
author_sort O’Connor, Charles Joseph
collection PubMed
description INTRODUCTION AND OBJECTIVES: This Swiss LithoClast(®) Trilogy lithotrite is a new lithotrite for percutaneous nephrolithotomy (PCNL). It has four modifiable settings; impact, frequency, ultrasound and suction. We aim to determine the optimal device settings for the fastest stone clearance. MATERIALS AND METHODS: Kidney stone phantoms were made with Begostone in a powder to water ratio (15:3–15:6). Complete stone clearance (seconds) was calculated and impact and frequency were adjusted and repeated N = 3. Intra renal pressure (IRP) was then measured in a porcine kidney model. RESULTS: Stone phantoms with physical properties similar to struvite were cleared best with 100% impact and frequency of 12 Hz. Both uric acid stone phantoms and calcium phosphate stone phantoms were cleared most efficiently with an impact of 30% and a frequency of 4 Hz. The mean time to clear uric acid stone phantoms was 83 s versus 217 s for calcium phosphate stone phantoms. Similarly, for calcium oxalate stone phantoms, an impact of 30% and a frequency of 4 Hz was associated with the fastest clearance time, mean 204 s. However, the differences between 4, 8 and 12 Hz were not statistically significant. At a suction level of 60% or higher, IRP became negative. CONCLUSION: These results indicate that stone phantoms of hard kidney stones are cleared more efficiently at lower impact and frequency settings. With regard to suction, a setting of ≤ 50% appears to be the optimal setting.
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spelling pubmed-95127122022-09-28 An ex-vivo assessment of a new single probe triple modality (Trilogy) lithotripter O’Connor, Charles Joseph Hogan, Donnacha Yap, Lee Chien Lyons, Louise Hennessey, Derek Barry World J Urol Original Article INTRODUCTION AND OBJECTIVES: This Swiss LithoClast(®) Trilogy lithotrite is a new lithotrite for percutaneous nephrolithotomy (PCNL). It has four modifiable settings; impact, frequency, ultrasound and suction. We aim to determine the optimal device settings for the fastest stone clearance. MATERIALS AND METHODS: Kidney stone phantoms were made with Begostone in a powder to water ratio (15:3–15:6). Complete stone clearance (seconds) was calculated and impact and frequency were adjusted and repeated N = 3. Intra renal pressure (IRP) was then measured in a porcine kidney model. RESULTS: Stone phantoms with physical properties similar to struvite were cleared best with 100% impact and frequency of 12 Hz. Both uric acid stone phantoms and calcium phosphate stone phantoms were cleared most efficiently with an impact of 30% and a frequency of 4 Hz. The mean time to clear uric acid stone phantoms was 83 s versus 217 s for calcium phosphate stone phantoms. Similarly, for calcium oxalate stone phantoms, an impact of 30% and a frequency of 4 Hz was associated with the fastest clearance time, mean 204 s. However, the differences between 4, 8 and 12 Hz were not statistically significant. At a suction level of 60% or higher, IRP became negative. CONCLUSION: These results indicate that stone phantoms of hard kidney stones are cleared more efficiently at lower impact and frequency settings. With regard to suction, a setting of ≤ 50% appears to be the optimal setting. Springer Berlin Heidelberg 2022-08-24 2022 /pmc/articles/PMC9512712/ /pubmed/36001137 http://dx.doi.org/10.1007/s00345-022-04127-8 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article
O’Connor, Charles Joseph
Hogan, Donnacha
Yap, Lee Chien
Lyons, Louise
Hennessey, Derek Barry
An ex-vivo assessment of a new single probe triple modality (Trilogy) lithotripter
title An ex-vivo assessment of a new single probe triple modality (Trilogy) lithotripter
title_full An ex-vivo assessment of a new single probe triple modality (Trilogy) lithotripter
title_fullStr An ex-vivo assessment of a new single probe triple modality (Trilogy) lithotripter
title_full_unstemmed An ex-vivo assessment of a new single probe triple modality (Trilogy) lithotripter
title_short An ex-vivo assessment of a new single probe triple modality (Trilogy) lithotripter
title_sort ex-vivo assessment of a new single probe triple modality (trilogy) lithotripter
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9512712/
https://www.ncbi.nlm.nih.gov/pubmed/36001137
http://dx.doi.org/10.1007/s00345-022-04127-8
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