Structural insights into molecular mechanism for N(6)-adenosine methylation by MT-A70 family methyltransferase METTL4

METTL4 belongs to a subclade of MT-A70 family members of methyltransferase (MTase) proteins shown to mediate N(6)-adenosine methylation for both RNA and DNA in diverse eukaryotes. Here, we report that Arabidopsis METTL4 functions as U2 snRNA MTase for N(6)−2’-O-dimethyladenosine (m(6)Am) in vivo tha...

Descripción completa

Detalles Bibliográficos
Autores principales: Luo, Qiang, Mo, Jiezhen, Chen, Hao, Hu, Zetao, Wang, Baihui, Wu, Jiabing, Liang, Ziyu, Xie, Wenhao, Du, Kangxi, Peng, Maolin, Li, Yingping, Li, Tianyang, Zhang, Yangyi, Shi, Xiaoyan, Shen, Wen-Hui, Shi, Yang, Dong, Aiwu, Wang, Hailin, Ma, Jinbiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9512776/
https://www.ncbi.nlm.nih.gov/pubmed/36163360
http://dx.doi.org/10.1038/s41467-022-33277-x

Ejemplares similares

Ejemplares similares