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A dual Keap1 and p47(phox) inhibitor Ginsenoside Rb1 ameliorates high glucose/ox-LDL-induced endothelial cell injury and atherosclerosis

Oxidative stress is a vital contributor to the development and progression of diabetes-accelerated atherosclerosis. Nuclear factor erythroid 2-related factor 2 (Nrf2) is a well-known molecule that participates in cellular defense against oxidative stress. Utilizing luciferase reporter assay from 379...

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Detalles Bibliográficos
Autores principales: Wang, Zi-Chao, Niu, Kai-Ming, Wu, Yu-Jie, Du, Kai-Rui, Qi, Lian-Wen, Zhou, Ye-Bo, Sun, Hai-Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9512801/
https://www.ncbi.nlm.nih.gov/pubmed/36163178
http://dx.doi.org/10.1038/s41419-022-05274-x