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A dual Keap1 and p47(phox) inhibitor Ginsenoside Rb1 ameliorates high glucose/ox-LDL-induced endothelial cell injury and atherosclerosis
Oxidative stress is a vital contributor to the development and progression of diabetes-accelerated atherosclerosis. Nuclear factor erythroid 2-related factor 2 (Nrf2) is a well-known molecule that participates in cellular defense against oxidative stress. Utilizing luciferase reporter assay from 379...
Autores principales: | Wang, Zi-Chao, Niu, Kai-Ming, Wu, Yu-Jie, Du, Kai-Rui, Qi, Lian-Wen, Zhou, Ye-Bo, Sun, Hai-Jian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9512801/ https://www.ncbi.nlm.nih.gov/pubmed/36163178 http://dx.doi.org/10.1038/s41419-022-05274-x |
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