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Modeling tissue-specific breakpoint proximity of structural variations from whole-genomes to identify cancer drivers
Structural variations (SVs) in cancer cells often impact large genomic regions with functional consequences. However, identification of SVs under positive selection is a challenging task because little is known about the genomic features related to the background breakpoint distribution in different...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9512825/ https://www.ncbi.nlm.nih.gov/pubmed/36163358 http://dx.doi.org/10.1038/s41467-022-32945-2 |