Motor unit number index (MUNIX) in the D50 disease progression model reflects disease accumulation independently of disease aggressiveness in ALS

The neurophysiological technique motor unit number index (MUNIX) is increasingly used in clinical trials to measure loss of motor units. However, the heterogeneous disease course in amyotrophic lateral sclerosis (ALS) obfuscates robust correlations between clinical status and electrophysiological as...

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Detalles Bibliográficos
Autores principales: Ebersbach, Theresa, Roediger, Annekathrin, Steinbach, Robert, Appelfeller, Martin, Tuemmler, Anke, Stubendorff, Beatrice, Schuster, Simon, Herdick, Meret, Axer, Hubertus, Witte, Otto W., Grosskreutz, Julian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9512899/
https://www.ncbi.nlm.nih.gov/pubmed/36163485
http://dx.doi.org/10.1038/s41598-022-19911-0

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