Graphdiyne oxide nanosheets display selective anti-leukemia efficacy against DNMT3A-mutant AML cells

DNA methyltransferase 3 A (DNMT3A) is the most frequently mutated gene in acute myeloid leukemia (AML). Although chemotherapy agents have improved outcomes for DNMT3A-mutant AML patients, there is still no targeted therapy highlighting the need for further study of how DNMT3A mutations affect AML ph...

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Detalles Bibliográficos
Autores principales: Wang, Qiwei, Liu, Ying, Wang, Hui, Jiang, Penglei, Qian, Wenchang, You, Min, Han, Yingli, Zeng, Xin, Li, Jinxin, Lu, Huan, Jiang, Lingli, Zhu, Meng, Li, Shilin, Huang, Kang, Tang, Mingmin, Wang, Xinlian, Yan, Liang, Xiong, Zecheng, Shi, Xinghua, Bai, Ge, Liu, Huibiao, Li, Yuliang, Zhao, Yuliang, Chen, Chunying, Qian, Pengxu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9512932/
https://www.ncbi.nlm.nih.gov/pubmed/36163326
http://dx.doi.org/10.1038/s41467-022-33410-w

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