Preventing SARS-CoV-2 Infection Using Anti-spike Nanobody-IFN-β Conjugated Exosomes

PURPOSE: To inhibit the transmission of SARS-CoV-2, we developed engineered exosomes that were conjugated with anti-spike nanobodies and type I interferon β (IFN-β). We evaluated the efficacy and potency of nanobody-IFN-β conjugated exosomes to treatment of SARS-CoV-2 infection. METHODS: Milk fat gl...

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Detalles Bibliográficos
Autores principales: Lyu, Xiabing, Imai, Shota, Yamano, Tomoyoshi, Hanayama, Rikinari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9512977/
https://www.ncbi.nlm.nih.gov/pubmed/36163411
http://dx.doi.org/10.1007/s11095-022-03400-0

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